Results 101 to 110 of about 138,899 (263)

Old Spanish Trail Association Collection

open access: yes, 2017
The Old Spanish Trail Association Collection is divided into two series, historic and administrative. The historic papers include: newsletters, correspondence, research, map and trail guides, publications and administrative files.
Old Spanish Trail Association
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Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Buckeye Trail Association members at the Grandma Gatewood Memorial Hiking Trail

open access: yes, 1984
Emily Gregor and Ann Quadrano, members of the Buckeye Trail Association, shown standing at the memorial marking the entrance to the Grandma Gatewood Memorial Hiking Trail in Hocking County, Ohio.

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Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Souvenir postcard of Trail

open access: yes, 1951
Taken from West Trail looking across the Columbia River towards East ...

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Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

Ionizable Lipid Nanoparticle-Mediated TRAIL mRNA Delivery in the Tumor Microenvironment to Inhibit Colon Cancer Progression

open access: yesInternational Journal of Nanomedicine
Walison Nunes da Silva,1 Pedro Augusto Carvalho Costa,1 Sérgio Ricardo Aluotto Scalzo Júnior,1 Heloísa AS Ferreira,1 Pedro Henrique Dias Moura Prazeres,2 Caroline Leonel Vasconcelos Campos,3 Marco Túllio Rodrigues Alves,1 Natália Jordana Alves da Silva,1
da Silva WN   +22 more
doaj  

Trail, B.C.

open access: yes, 1913
Trail in 1913, with 1895 ...

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On the Trail of Prometheus

open access: yesChemistry & Biology, 2006
The Greek gods punished Prometheus for giving their fire to humans. Each day, an eagle would tear out his liver; every night it would grow back again. Although bodily regeneration has existed in myth for millennia, only certain tissues will, in fact, regenerate. Over the last two decades, many companies have tried to transform regenerative ability into
openaire   +2 more sources

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