Results 41 to 50 of about 395,211 (318)

Differential activation of JNK1 isoforms by TRAIL receptors modulate apoptosis of colon cancer cell lines

, 2009
Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) induces apoptosis on binding to its receptors, death receptor 4 and 5 (DR4, DR5).
M Keane, Mehmet, H, A Samali, D Mahalingam, H Mehmet, Mahalingam, D, E Szegezdi, Szegezdi, E, Keane, M, G Pirianov, Pirianov, G, Samali, A   +11 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

Some new results on the travelling salesman problem

Vallis Aurea, 2015
The travelling salesman problem (or The sales representative problem) has been insufficiently explored so far. One of the first results on this issue was provided by Euler in 1759 (The problem of moving a knight on the chess board), Knight's Tour Problem.
Dominika Crnjac Milić, Ljiljanka Kvesić   +1 more
doaj   +1 more source

In the footsteps of Joseph II. The potential of the new tourist route of the countries of the former Habsburg Empire from the perspective of cultural heritage tourism

Baltic Journal of Health and Physical Activity, 2021
Background: The aim of the article is to present the tourist potential of the routes of rulers’ journeys in the territories of modern countries belonging to former empires.
Agnieszka Bogdal-Brzezinska
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Dalgleish scores difference amongst professional roles within the greater child welfare community

Child Protection and Practice
Background: The central tension of the child welfare system is the need to protect children while also encouraging the stability of families. Researchers have attempted to capture this conflict through the use of the Dalgleish Scale (Fluke et al., 2016),
Matthew Trail
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

TP53INP2 at the crossroad of apoptosis and autophagy in death receptor signaling

Molecular & Cellular Oncology, 2019
The binding of ligands to death receptors elicits distinct outcomes, such as apoptosis, inflammation and necroptosis, depending on the cellular context. We have recently described that the autophagic protein TP53INP2 favors apoptosis upon death receptor ...
Saška Ivanova, Antonio Zorzano
doaj   +1 more source

Connection and separation in hypergraphs

Theory and Applications of Graphs, 2015
In this paper we study various fundamental connectivity properties of hypergraphs from a graph-theoretic perspective, with the emphasis on cut edges, cut vertices, and blocks. We prove a number of new results involving these concepts.
Mohammad Bahmanian, Mateja Sajna
doaj   +1 more source