Results 101 to 110 of about 1,435,170 (249)
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
THE EFFECTIVENESS OF THE SYSTEMS OF DISTRIBUTED CONTROL THE SPEED OF THE CARS AT THE SORTING PATHS
Nauka ta progres transportu, 2010 The use of systems of the quasi–continuous adjusting the wagon speed on the marshalling tracks contributes to the improvement of indices of occupation quality of marshalling tracks with wagons. These indices characterize different sides of the occupation
O. A. Nazarov
doaj
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Train Network Control System and Its Fault Diagnosis of Guangzhou Metro Line 3
机车电传动, 2012 Taking Guangzhou metro line 3 as an example, train network control system and its diagnosis were analyzed. Based on the Guangzhou metro line 3 train network control system troubleshooting and analysis, higher requirements of the train network control ...
HUANGWen-can
doaj
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Application Analysis of CTCS-3 in City Railway
Chengshi guidao jiaotong yanjiuObjective At present, there is still no practical case of using CTCS 3 (Chinese Train Control System Level 3) in city railway in China. The application of CTCS-3 system in city railway should be explored to expand its application in urban railway. Method
QUAN Hongyu
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Nonlinear PID Control for Levitation System of Maglev Train
机车电传动, 2014 Aim to the shortages of traditional PID levitation controller for maglev train, PID controller characteristic was analyzed, andnonlinear PID controller considering system error parameters was designed to realize system stable levitation.
CHEN Qiang, LI Xiao-long, LIU Shao-ke
doaj
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source