Results 61 to 70 of about 210,711 (264)
Kongzhi Yu Xinxi Jishu, 2020 The lately released Subset 037 with ERTMS B3R2 introduces the concept and the trend of packet switch in train control system. The importance of train control packet domain communication was firstly summarized, and the PS and CS domain allocation method ...
LIU Zhenyu, SONG Yan, QU Yongzheng
doaj
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Communication network-based train control system
机车电传动The automatic configuration (inauguration) of train communication networks (TCN) is emphasized as a distinguishing feature of train control and management systems (TCMS).
LU Xiangyang +5 more
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Innovative Research and Implementation of High-speed Train Network Control System for CRH2
机车电传动, 2014 CRH2 high-speed train network topology and train transport protocol were introduced, and independent high-speed train network control software system architecture and network control system logic functions was described in detail.
HUO Fang, LIU Qun-xin, ZHANG Sen
doaj
Scheme Research on Train Operation Control System Supporting Virtual Marshalling Technology
Chengshi guidao jiaotong yanjiuObjective With the development of urban rail transit network, the uneven temporal and spatial distribution characteristic of the network passenger flow is growing prominent, and it is difficult to achieve the "on-demand transportation " with the existing
ZHANG Yang +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
TRAINING SYSTEM OF FUTURE SPECIALISTS: QUALITY CONTROL
The Education and science journal, 2015 The aim of the investigation is development of innovative strategy of quality control training of engineers and skilled workers (hereinafter – future specialists) in educational professional organizations on the principles of social partnership.Methods. Theoretic: theoretic and methodological analysis, polytheoretic synthesis, modeling.
ROMANOV VLADIMIR A. +2 more
openaire +4 more sources