Results 41 to 50 of about 210,711 (264)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Research on Fully Automatic Operation Technology in Case of ATO Equipment Failure
Kongzhi Yu Xinxi Jishu, 2021 At present, in a fully automatic operation (FAO) system of urban rail transit, train operation is highly dependent on the automatic train operation (ATO) system as there is no driver in the train.
YIN Yihui, LEI Chengjian, LIU Ze
doaj
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Medium-low Speed Maglev Train Control and Network System
机车电传动, 2012 Design and configuration of network control system for medium-low speed maglev train were presented. Network control system was described from system bus, topology, and functions, etc.
SU Ai-jun +4 more
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Metro Train Braking Simulation Control System Based on EP2002 Braking System
Chengshi guidao jiaotong yanjiu[Objective] To address the issue of the highly integrated internal structure of the EP2002 valve system, which hinders internal fault injection, a metro train braking simulation control system that accurately reflects the functioning mechanism of the ...
Wenchuan ZHANG, Chenglian LANG
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Research on High-speed Train Control System Based on Ethernet
机车电传动, 2019 Because of the unique advantages of Ethernet in improving the efficiency of train maintenance, reducing maintenance costs and promoting train intellectualization, building intelligent control system based on Ethernet will be the development trend of ...
Yan XIONG, He HUANG, Siyuan LI, Qing XU
doaj
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source