Results 71 to 80 of about 5,805,357 (277)

From novice to expert: preparing your peer review

open access: yesmBio
Peer review is the process by which the quality of scholarly work is assessed prior to being published, presented, or funded. The consequences of flawed research entering the public domain in the “post-truth” era highlight the need to improve peer review
Diana M. Proctor   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

International Recommendations on Education in Biomedical and Health Informatics – An Overview

open access: yesApplied Medical Informatics, 2023
The educational recommendations aim is to provide a tool for academic program evaluators to compare and accredit the quality of delivered programs; support educators in developing BMHI (Biomedical and Health Informatics) curricula at various educational ...
John MANTAS
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Enhancing radiation protection at Sirius: methodology and results of beamline training

open access: yesBrazilian Journal of Radiation Sciences
This work is about radiation protection training at Sirius, a unique radiation facility in Brazil for being a synchrotron-type particle accelerator. Research in several areas takes place at the facility, attracting researchers from all over the world ...
Ana Luísa da Costa Vieira   +1 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Satisfying national and individual interests: impact evaluation of the KOICA master’s degree scholarship program

open access: yesJournal of Contemporary East Asia Studies
Precisely measuring the impact of official development assistance (ODA) programs is considered important, however, it has been a challenge for practitioners and politicians because of the lack of available data.
Kyuwon Kang, Junhyup Kim, Do Won Kwak
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Assessment of biosafety training and practices in biomedical laboratories in Kinshasa, Democratic Republic of the Congo

open access: yesOrapuh Journal
Introduction In biomedical laboratories, biosafety is a key element for preventing infections and ensuring the safety of healthcare workers and the community.
Diane Sare Gamani   +5 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

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