Results 81 to 90 of about 12,829,090 (362)
Not the peace train but the piece train
CITATION: Nasson, B. 2020. Not the peace train but the piece train. South African Journal of Science, 116(5/6):8136, doi:10.17159/sajs.2020/8136.
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A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp+13 more
wiley +1 more source
BACKGROUND: We hypothesized that knowledge regarding obstetric anal sphincter injuries amongst healthcare workers in our setting is limited. A lack of knowledge would result in worsened clinical outcomes and proving this knowledge deficiency would allow ...
Randall Kegan Hammond, MbChB, FCOG, MMed+1 more
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The subject of this article is export of higher education services, which becomes an increasingly important part of social and economic development in various countries across the world.
Oleg L. Verevkin
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Are doctors in training being trained? [PDF]
1512 www.thelancet.com Vol 387 April 9, 2016 highest educational value score. An unfortunate disconnect clearly exists between the educational value of a task and how much time is spent on it, because trainees are spending a substantial amount of time on activities that are perceived as having the lowest educational value.
Mathews, John Abraham+2 more
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C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald+18 more
wiley +1 more source
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner+6 more
wiley +1 more source
The Use of New Technologies for Improving Reading Comprehension
Since the introduction of writing systems, reading comprehension has always been a foundation for achievement in several areas within the educational system, as well as a prerequisite for successful participation in most areas of adult life.
Agnese Capodieci+4 more
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Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon+13 more
wiley +1 more source
Winceslaus Katagira,1 Amy V Jones,2,3 Mark W Orme,2,3 Zainab K Yusuf,2,3 Pauline Ndagire,1 Jaliah Nanyonga,1 Richard Kasiita,4 Josephine N Kasolo,5 Ruhme B Miah,2,3 Michael C Steiner,2,3 Rupert Jones,6 Andy Barton,2 Bruce Kirenga,1 Sally J Singh2,3 ...
Katagira W+13 more
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