Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Greater Neural Adaptations following High- vs. Low-Load Resistance Training
Frontiers in Physiology, 2017 We examined the neuromuscular adaptations following 3 and 6 weeks of 80 vs. 30% one repetition maximum (1RM) resistance training to failure in the leg extensors.
Nathaniel D. M. Jenkins +7 more
doaj +1 more source
A comparison between a traditionally periodised programme and a load autoregulated periodised programme for maximal strength gain in the squat, bench press, and deadlift in weight-trained males : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Exercise and Sport Science at Massey University, Manawatū, New Zealand [PDF]
, 2016 Background: Training towards the goal of improving maximal strength is commonly undertaken; particularly by athletes involved in contact sports, powerlifters, and recreational body builders.
Fraser, Jeremy
core
Inductive machine learning of optimal modular structures: Estimating solutions using support vector machines [PDF]
, 2007 Structural optimization is usually handled by iterative methods requiring repeated samples of a physics-based model, but this process can be computationally demanding.
Hanna, S.
core +1 more source
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Optimizing Team Sport Training With Multi-Objective Evolutionary Computation
International Journal of Computer Science in Sport, 2021 This research introduces a new novel method for mathematically optimizing team sport training models to enhance two measures of athletic performance using an evolutionary computation based approach.
Connor Mark +4 more
doaj +1 more source
Effect of front and back squat techniques on peak loads experienced by the Achilles tendon [PDF]
, 2015 Background A primary technique in the discipline of strength and conditioning the squat has two principal ‘back and front’ variants. Despite the physiological and strength benefits of the squat, the propensity for musculoskeletal injury is high.
Atkins, Stephen +4 more
core
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Competition Stress Prolongs Exercise Recovery in Female Division I Collegiate Soccer Players
SportsThis study examined the effect of competition stress on recovery time in female collegiate soccer players. Thirty NCAA Division I athletes were monitored over 35 consecutive days using Polar Team Pro wearable devices, which captured exercise duration ...
Courtney D. Jensen +3 more
doaj +1 more source
Interval training normalizes cCardiomyocyte function, diastolic Ca2+ control, and SR Ca2+ release synchronicity in a mouse model of diabetic cardiomyopathy [PDF]
, 2009 In the present study we explored the mechanisms behind excitation-contraction (EC)-coupling defects in cardiomyocytes from mice with type-2 diabetes (db/db), and determined whether 13-weeks of aerobic interval training could restore cardiomyocyte Ca2 ...
Aasum, E. +10 more
core +2 more sources