Results 101 to 110 of about 956,231 (273)

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

I-PASS Mentored Implementation Handoff Curriculum: Frontline Provider Training Materials. [PDF]

MedEdPORTAL, 2020
O'Toole JK, Hepps J, Starmer AJ, Patel SJ, Rosenbluth G, Calaman S, Campos ML, Lopreiato JO, Schnipper JL, Sectish TC, Srivastava R, West DC, Landrigan CP, Spector ND, Yu CE, I-PASS Study Education Executive Committee.   +15 more
europepmc   +1 more source

2012-10-23 Astronomy Dataverse Workshop Training Materials

, 2012
August Muench
openalex   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

The Effect of Two-Step Austempering Temperature and Copper Addition on the Microstructure and Mechanical Properties of ADI

مواد نوین
This study investigated the influence of copper addition and two-step austempering temperature on the microstructure, phase fractions, and mechanical properties of austempered ductile iron (ADI).
Mehdi Ghorbani Jamal-Abadi, Amir Abedi, Soroush Parvizi, Mina Safa, Saloumeh Mesgari Abbasi, Gholamreza Khalaj   +5 more
doaj  

Manuals, guidelines and toolkits to support the elimination of blinding trachoma

Community Eye Health Journal, 2016
The year 2020 is the target date for the elimination of blinding trachoma as a public health problem. There has been great progress, and there is unprecedented funding available – particularly from DFID, the Queen Elizabeth Diamond Jubilee Trust, and ...
Paul Courtright , Chad MacArthur
doaj  

Polarimeters for the Detection of Anisotropy from Reflectance

Micromachines
Polarimetry is used to determine the Stokes parameters of a laser beam. Once all four S0,1,2,3 parameters are determined, the state of polarisation is established.
Shuji Kamegaki, Zahra Khajehsaeidimahabadi, Meguya Ryu, Nguyen Hoai An Le, Soon Hock Ng, Ričardas Buividas, Gediminas Seniutinas, Vijayakumar Anand, Saulius Juodkazis, Junko Morikawa   +9 more
doaj   +1 more source

A Picture is Worth a Thousand Words: The Role of Survey Training Materials in Stated-Preference Studies. [PDF]

Patient, 2020
Vass CM, Davison NJ, Vander Stichele G, Payne K.   +3 more
europepmc   +1 more source

ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan, Yan Jiang, Yuxuan Yong, Tianshuo Zhang, Niannian Zhang, Qianqian Zeng, Xue Gong, Li Meng, Fangfang Bi, Yongmin Liu   +9 more
wiley   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source