Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Investigation of physical and mechanical performance of wood-based composites after laboratory accelerated aging [PDF]
The aim of current study is to determine the physical and mechanical properties of wood-based composites commonly used in Iran’s market before and after accelerated aging. Accelerated aging process performed based on ASTM D1037.
Samaneh Yousefi Lonbar +2 more
doaj
Application of Taguchi Method for Investigating the Mechanical Properties of a Microalloyed Steel
In the present investigation, the effects of processing parameters, such as roughing, finishing and coiling temperatures, on the strain hardening exponent and yield strength of a Nb-microalloyed steel has been studied by Taguchi method.
Ayaz M. +2 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
Known Unknowns: Out-of-Distribution Property Prediction in Materials and Molecules [PDF]
Discovery of high-performance materials and molecules requires identifying extremes with property values that fall outside the known distribution. Therefore, the ability to extrapolate to out-of-distribution (OOD) property values is critical for both ...
Nofit Segal +4 more
semanticscholar +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
The learning with care training materials
Outlines the content of the Learning with Care training materials, commissioned by the Scottish Executive through the Learning with Care project. The materials were sent to every local authority and residential child care provider in Scotland, with many ...
Judy Furnivall, Barbara Hudson
doaj +1 more source
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura +19 more
wiley +1 more source
A comparative study of the effects of multimedia training materials on mini CEX scores of internal medicine residents in Isfahan University of Medical Sciences. [PDF]
Shokrollahi S +4 more
europepmc +1 more source

