Results 81 to 90 of about 14,557,136 (249)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Investigation of physical and mechanical performance of wood-based composites after laboratory accelerated aging [PDF]

open access: yesIranian Journal of Wood and Paper Industries, 2018
The aim of current study is to determine the physical and mechanical properties of wood-based composites commonly used in Iran’s market before and after accelerated aging. Accelerated aging process performed based on ASTM D1037.
Samaneh Yousefi Lonbar   +2 more
doaj  

Application of Taguchi Method for Investigating the Mechanical Properties of a Microalloyed Steel

open access: yesArchives of Metallurgy and Materials, 2014
In the present investigation, the effects of processing parameters, such as roughing, finishing and coiling temperatures, on the strain hardening exponent and yield strength of a Nb-microalloyed steel has been studied by Taguchi method.
Ayaz M.   +2 more
doaj   +1 more source

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

open access: yesFEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj   +3 more
wiley   +1 more source

Known Unknowns: Out-of-Distribution Property Prediction in Materials and Molecules [PDF]

open access: yesnpj Computational Materials
Discovery of high-performance materials and molecules requires identifying extremes with property values that fall outside the known distribution. Therefore, the ability to extrapolate to out-of-distribution (OOD) property values is critical for both ...
Nofit Segal   +4 more
semanticscholar   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

open access: yesFEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho   +4 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

open access: yesFEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour   +2 more
wiley   +1 more source

The learning with care training materials

open access: yesScottish Journal of Residential Child Care, 2003
Outlines the content of the Learning with Care training materials, commissioned by the Scottish Executive through the Learning with Care project. The materials were sent to every local authority and residential child care provider in Scotland, with many ...
Judy Furnivall, Barbara Hudson
doaj   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

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