Results 31 to 40 of about 956,231 (273)

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

Lay-interviewer training protocol for the WHO Flexible Interview for ICD-11 for the National Mental Health Survey – 2 (India)

Indian Journal of Psychiatry
Background: The National Mental Health Survey-2 (NMHS-2) of India is to be conducted in 2024–2026, across the country with over 2,25,000 individual assessments.
Lakshmi Jogi, Harsh Khandelwal, Avani Sharma, Niharika Singh, T. S Jaisoorya, Geoffrey M. Reed, Karen T. Maré, Girish N. Rao, Vivek Benegal   +8 more
doaj   +1 more source

Evaluating the Possibility of Replacing Non-Wood Core in the Make of Wooden Sandwich Panel to Reduce the Consumption of Wood Resources, Preserve the Environment and Human Health [PDF]

محیط زیست و توسعه فرابخشی
Introduction: Given the increase in the world's population and the subsequent increase in demand for wood and wood products, the high cost of wood, limited forest resources, damage to forests, the environment, and human health, today it is very important
Pantea Omrani, Hosein Rangavar, Afshin Rahmati Tula Rud-e Pain   +2 more
doaj   +1 more source

Instructional Design Framework for Construction Materials Training

Frontiers in Built Environment, 2022
The construction industry is suffering, in part, from a lack of training programs offered to the construction workforce. Unfortunately, most construction training and education research focuses on university student education.
Hazem Jadallah, Carol J. Friedland, Isabelina Nahmens, Charles Pecquet, Charles Berryman, Yimin Zhu   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Application of conjugated materials in sports training

Frontiers in Chemistry, 2023
In recent years, with the rapid development of the sports industry, the quality of sports training products on the market is uneven. Problems such as inaccurate detection of athletes’ physical indicators, low comfort of sportswear, and reduced ...
Kun Zhu, Longfei Zhao
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Fresnel incoherent correlation holography with single camera shot

Opto-Electronic Advances, 2020
Fresnel incoherent correlation holography (FINCH) is a self-interference based super-resolution three-dimensional imaging technique. FINCH in inline configuration requires an active phase modulator to record at least three phase-shifted camera shots to ...
Vijayakumar Anand, Katkus Tomas, Lundgaard Stefan, Linklater Denver P., Ivanova Elena P., Ng Soon Hock, Juodkazis Saulius   +6 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source