Results 51 to 60 of about 993,302 (224)
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
FEBS Open Bio, EarlyView.Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao +3 more
wiley +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
RUDN Journal of Informatization in Education, 2020 Problem and goal. The article describes how to organize electronic training materials for post-training support. The relevance of the article is determined, on the one hand, by the external needs to expand the sphere of education, the tasks of further ...
Olga Yu. Zaslavskaya, Maya S. Levchenko
doaj +1 more source
Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum
FEBS Open Bio, EarlyView.Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
npj Materials DegradationIn this study, equilibrium and non-equilibrium (Scheil) solidification phase diagrams were simulated to identify an optimised AlxCrFeNiSiy high-entropy alloy (HEA) composition aimed at promoting simple solid-solution phases while minimising undesirable ...
Michael Boschen +5 more
doaj +1 more source
Investigation of physical and mechanical performance of wood-based composites after laboratory accelerated aging [PDF]
Iranian Journal of Wood and Paper Industries, 2018 The aim of current study is to determine the physical and mechanical properties of wood-based composites commonly used in Iran’s market before and after accelerated aging. Accelerated aging process performed based on ASTM D1037.
Samaneh Yousefi Lonbar +2 more
doaj
Wedge Surface Plasmon Polariton Waveguides Based on Wet-Bulk Micromachining
Photonics, 2019 In this paper, we propose and investigate the modal characteristics of wedge surface plasmon polariton (SPP) waveguides for guiding surface plasmon waves.
Nguyen Thanh Huong +2 more
doaj +1 more source