Results 31 to 40 of about 993,302 (224)

Lay-interviewer training protocol for the WHO Flexible Interview for ICD-11 for the National Mental Health Survey – 2 (India)

open access: yesIndian Journal of Psychiatry
Background: The National Mental Health Survey-2 (NMHS-2) of India is to be conducted in 2024–2026, across the country with over 2,25,000 individual assessments.
Lakshmi Jogi   +8 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Evaluating the Possibility of Replacing Non-Wood Core in the Make of Wooden Sandwich Panel to Reduce the Consumption of Wood Resources, Preserve the Environment and Human Health [PDF]

open access: yesمحیط زیست و توسعه فرابخشی
Introduction: Given the increase in the world's population and the subsequent increase in demand for wood and wood products, the high cost of wood, limited forest resources, damage to forests, the environment, and human health, today it is very important
Pantea Omrani   +2 more
doaj   +1 more source

Instructional Design Framework for Construction Materials Training

open access: yesFrontiers in Built Environment, 2022
The construction industry is suffering, in part, from a lack of training programs offered to the construction workforce. Unfortunately, most construction training and education research focuses on university student education.
Hazem Jadallah   +5 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Fresnel incoherent correlation holography with single camera shot

open access: yesOpto-Electronic Advances, 2020
Fresnel incoherent correlation holography (FINCH) is a self-interference based super-resolution three-dimensional imaging technique. FINCH in inline configuration requires an active phase modulator to record at least three phase-shifted camera shots to ...
Vijayakumar Anand   +6 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Crystallization and magnetic characterizations of DyIG and HoIG nanopowders fabricated using citrate sol-gel

open access: yesJournal of Science: Advanced Materials and Devices, 2016
Dy and Ho iron garnets in form of nanoparticles were synthesized by citrate sol-gel method. Phase formation, lattice constant and average crystallite sizes of the samples were determined via XRD measurements.
Dao Thi Thuy Nguyet   +5 more
doaj   +1 more source

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