Results 111 to 120 of about 18,365,520 (343)

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source

Academic anaesthesiology: a global perspective on training, support, and future development of early career researchers. [PDF]

Br J Anaesth, 2023
Stundner O, Adams MCB, Fronczek J, Kaura V, Li L, Allen ML, Vail EA.   +6 more
europepmc   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Retracted: Differentially Private Singular Value Decomposition for Training Support Vector Machines. [PDF]

Comput Intell Neurosci, 2023
Intelligence And Neuroscience C.
europepmc   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Flowering-Stage Heat Stress Assessment in Summer Maize Using Multi-Source Data and Machine Learning

Advances in Meteorology
Flowering-stage heat stress in summer maize (Zea mays L.) can substantially reduce grain number per ear (GNP), yet traditional assessments based on daily temperature or single indicators often fail to capture short-duration extreme events and their ...
Junling Li, Mengxia Li, Shuyan Li, Jiabu Zhou, Wanlin Dong, Changying Xue, Qile Guo   +6 more
doaj   +1 more source

miR-374c-5p reduces hydrogen peroxide induced apoptosis of human umbilical vein endothelial cells [PDF]

Jichu yixue yu linchuang
Objective To explore the protective effect of miR-374c-5p on hydrogen peroxide (H2O2) -induced apoptosis of human umbilical vein endothelial cells (HUVECs).
JIA Zonghu, JIN Qun, HAN Shufang, HU Yuhong, REN Changzhen, LI Yunping, LIU Wenyan
doaj   +1 more source

Research productivity and training support for doctoral students in the biological and biomedical sciences. [PDF]

FASEB Bioadv, 2023
Schaller MD.
europepmc   +1 more source

Leadership for Learning: Making the Connections Among State, District, and School Policies and Practices [PDF]

, 2006
Demonstrates the critical need for systematic policies, standards, and training that support elementary and secondary school principals in their roles as effective leaders and catalysts of student ...

core  

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source