Results 121 to 130 of about 18,365,520 (343)

Deep Features for Training Support Vector Machines. [PDF]

open access: yesJ Imaging, 2021
Nanni L, Ghidoni S, Brahnam S.
europepmc   +1 more source

Emergency life support training for school children: exploring local implementation and outcomes of the Heartstart UK school programme within the context of the National Healthy School Standard [PDF]

open access: yes, 2005
This project discusses the implementation of Heartstart UK - an initiative co-ordinated by the British Heart Foundation to increase emergency life support training - in a number of schools in Cheshire.British Heart ...
May, Stephanie, Thurston, Miranda
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Support Vector Neural Training [PDF]

open access: yes, 2005
SVM learning strategy based on progressive reduction of the number of training vectors is used for MLP training. Threshold for acceptance of useful vectors for training is dynamically adjusted during learning, leading to a small number of support vectors near decision borders and higher accuracy of the final solutions.
openaire   +1 more source

AN INVESTIGATIONAL RESEARCH ON THE CORRELATION BETWEEN THE MANAGER‘S ROLE IN TRAINING PROGRAMS AND TRAINING TRANSFER IN A LOCAL GOVERNMENT OFFICE IN MALAYSIA [PDF]

open access: yes
This research was designed to investigate the correlation between manager‘s role andtraining transfer. A survey method was employed to gather 427 usable questionnaires fromgovernment servants in a local government office in Malaysia.
Ali Fazilatulaili   +3 more
core  

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