Results 51 to 60 of about 5,764,573 (295)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

AN EVALUATION OF PRE-SERVICE TRAINING ON THE PERFORMANCE OF AGRICULTURE FACULTY STUDENTS, MANSOURA UNIVERSITY IN THE TRANSFER OF EXTENSION KNOWLEDGE TO THEIR PEERS IN PUBLIC HEALTH FIELD [PDF]

Arab Universities Journal of Agricultural Sciences, 2018
The study aimed to identify an evaluation of pre-service training on the performance of agriculture Faculty students, Mansoura University in the transfer of extension knowledge to their peers in public health field.
Amira Ramadan, Raghda Salem
doaj   +1 more source

Training and transfer of training in the search for camouflaged targets [PDF]

Attention, Perception, & Psychophysics, 2009
How do observers become proficient at finding camouflaged targets? Does gaining proficiency in locating a target in one camouflage search situation improve performance in novel camouflage situations? We examined these questions by having participants first perform a difficult camouflage search task for three sessions and, in the last session, search ...
Walter R, Boot, Mark B, Neider, Arthur F, Kramer   +2 more
openaire   +2 more sources

Maximizing the Impact and ROI of Leadership Development: A Theory- and Evidence-Informed Framework

Behavioral Sciences
Globally, organizations invest an estimated USD 60 billion annually in leadership development; however, the workplace application of learning is typically low, and many programs underperform or fail, resulting in wasted time and money and potential harm.
Jaason M. Geerts
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Can scope-of-practice transfer psychiatrists be up for their job? A cross-sectional study of clinical competence status and related factors

BMC Medical Education, 2022
Background The great economic and social changes have resulted in the prevalence of mental disorder increasing year by year in China. Mental health medical service resources of China are significantly insufficient.
Huan Wang, Zuowei Li, Ruoxin Fan, Shaoli Tian, Xianmei Yang   +4 more
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

Molecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh, Ji Yun Jang, Yoon Jeon, Gi‐Cheon Kim, Hwanho Lee, Jooyoung Lee, Ju‐Hwa Kim, Hakhyun Kim, Minjee Kim, Ho‐Keun Kwon, Ho Lee, Hyun Seok Kim   +11 more
wiley   +1 more source

The effects of Fe2O3 nanoparticles on physiology and insecticide activity in non-transgenic and Bt-transgenic cotton

Frontiers in Plant Science, 2016
As the demands for nanotechnology and nanoparticle (NP) applications in agriculture increase, the ecological risk has drawn more attention because of the unpredictable results of interactions between NPs and transgenic crops.
Nhan eLe Van, Nhan eLe Van, Chuanxin eMa, Rui eYukui, Weidong eCao, Yingqing eDeng, Liming eLiu, Baoshan eXing   +7 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Transfer of training in alphabet arithmetic [PDF]

Memory & Cognition, 2016
In recent years, several researchers have proposed that skilled adults may solve single-digit addition problems (e.g., 3 + 1 = 4, 4 + 3 = 7) using a fast counting procedure. Practicing a procedure, however, often leads to transfer of learning to unpracticed items; consequently, the fast counting theory was potentially challenged by subsequent studies ...
Jamie I D, Campbell, Yalin, Chen, Kurtis, Allen, Leah, Beech   +3 more
openaire   +2 more sources