Results 91 to 100 of about 1,857,161 (333)
Shared Genetic Effects and Antagonistic Pleiotropy Between Multiple Sclerosis and Common Cancers
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Epidemiologic studies have reported inconsistent altered cancer risk in individuals with multiple sclerosis (MS). Factors such as immune dysregulation, comorbidities, and disease‐modifying therapies may contribute to this variability.
Asli Buyukkurt +5 more
wiley +1 more source
A glimpse into the future composition of marine phytoplankton communities
Frontiers in Marine Science, 2014 It is expected that climate change will have significant impacts on ecosystems. Most model projections agree that the ocean will experience stronger stratification and less nutrient supply from deep waters.
Esteban eAcevedo-Trejos +6 more
doaj +1 more source
Depigmented wing patch size is a condition-dependent indicator of viability in male collared flycatchers [PDF]
, 2003 Honesty of sexual advertisement is thought to be the result of signalling costs. Because production costs of depigmented plumage patches are probably very low, their role as honest signals of individual quality has been questioned. Costs of bearing these
Garamszegi, László Zsolt +2 more
core +1 more source
Clustering Algorithm Reveals Dopamine‐Motor Mismatch in Cognitively Preserved Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore the relationship between dopaminergic denervation and motor impairment in two de novo Parkinson's disease (PD) cohorts. Methods n = 249 PD patients from Parkinson's Progression Markers Initiative (PPMI) and n = 84 from an external clinical cohort.
Rachele Malito +14 more
wiley +1 more source
Estimating disorder probability based on polygenic prediction using the BPC approach
Nature CommunicationsPolygenic Scores (PGSs) summarize an individual’s genetic propensity for a given trait. Bayesian methods, which improve the prediction accuracy of PGSs, are not well-calibrated for binary disorder traits in ascertained samples.
Emil Uffelmann +5 more
doaj +1 more source
Neurological Soft Signs in Schizophrenia: An Update on the State- versus Trait-Perspective
Frontiers in Psychiatry, 2018 BackgroundNeurological soft signs (NSS) represent minor neurological signs, which indicate non-specific cerebral dysfunction. In schizophrenia, their presence has been documented extensively across all stages of the disease.
Silke Bachmann +2 more
doaj +1 more source
Linking personality to cultural intelligence : an interactive effect of openness and agreeableness [PDF]
, 2015 The personality trait of openness is generally believed to influence an individual's cultural intelligence, which is an ability to deal effectively with people from different cultural backgrounds.
Kelly, Aidan +2 more
core +1 more source
Arthritis Care &Research, EarlyView.Objective Antinuclear antibodies (ANAs) are present at high titers in 2% of the general population, but their clinical significance in individuals without an autoimmune (AI) disease is not known. We tested the hypothesis that the presence of a high ANA titer in non‐AI conditions is associated with disease.
Matthew Chung +7 more
wiley +1 more source
3D Multicellular Scaffold Based Model for Advancing Bone Disorder Research
Advanced Functional Materials, EarlyView.A scalable 3D multicellular in vitro bone model engineered by integrating osteoblasts, osteoclasts, and endothelial cells on biodegradable scaffolds. The system recapitulates key features of human bone remodeling and disease pathology. As a proof of concept, the model mimics osteogenesis imperfecta, demonstrating its potential as a physiologically ...
Gali Guterman‐Ram +5 more
wiley +1 more source