Results 211 to 220 of about 716,573 (292)

Conversion of Transplanted Mature Hepatocytes into Afp+ Reprogrammed Cells for Liver Regeneration After Injury

Advanced Science, EarlyView.
Donor‐derived tdTomato+ mature hepatocytes were FACS‐isolated and transplanted into Fah−/− host mice. During regeneration, these cells convert into proliferative, unipotent Afp+ rHeps. Their plasticity is governed by a PPARγ/AFP‐dependent metabolic switch, segregating into pro‐proliferative Afplow and pro‐survival Afphigh subpopulations.
Ting Fang, Chao Yang, Hua Qiu, Yuan Du, Xicheng Wang, Yuting Li, Mingyang Xu, Changcheng Liu, Xiuhua Li, Na Guo, Jun Shi, Wencheng Zhang, Zhiying He   +12 more
wiley   +1 more source

Voluntary thalassemia screening: behaviours and constructs among youths from a thalassemia hot spot in Sri Lanka. [PDF]

BMC Res Notes
Yapa CN, Weerakoon NN, Tillakeratne TN, Amarasinghe GS.   +3 more
europepmc   +1 more source

Trait [PDF]

, 2019
openaire   +1 more source

Mapping Genetic Regulation of Transcription to Identify Functional Variants and Genes Associated with Pancreatic Cancer Risk

Advanced Science, EarlyView.
Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang, Hui Geng, Zhengyan Yao, Yuan Jiang, Can Chen, Zequn Lu, Shuangshuang Tian, Ming Zhang, Ruiyan Liu, Chenxi Feng, Bin Li, Xiaoping Miao, Jianbo Tian, Shaokai Zhang, Ying Zhu   +14 more
wiley   +1 more source

Author Correction: Reduced fungal protein acetylation mediates the antimicrobial activity of a rhizosphere bacterium against a phytopathogenic fungus

Nature Communications
Ying-Chao Zhang, Xin Zhan, Jun-Yu Chen, Ding-Tian Yu, Tao Zhang, Huiming Zhang, Cheng-Guo Duan   +6 more
doaj   +1 more source

Bayesian networks and structural equation models reveal genetic causal relationships between productivity, defense, and climate-adaptability traits in interior lodgepole pine. [PDF]

G3 (Bethesda)
Cappa EP, Klutsch JG, Benowicz A, Munilla S, Mansfield SD, Erbilgin N, Thomas BR, El-Kassaby YA.   +7 more
europepmc   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Early Childhood Anxiety and Maternal Factors: Associations with State and Trait Anxiety in a Greek Cohort of Preschoolers. [PDF]

Med Sci (Basel)
Angelakou EP, Papadopoulou SK, Pavlidou E, Louka A, Gerothanasi K, Giaginis C.   +5 more
europepmc   +1 more source

[Corrigendum] STAT3 activation in HER2‑overexpressing breast cancer promotes epithelial‑mesenchymal transition and cancer stem cell traits

Seyung Chung, Nolan Giehl, Yanyuan Wu, Jaydutt V. Vadgama   +3 more
openalex   +2 more sources

Attenuated Bacteria‐Based Tumor Therapy: Clinical Application Risks, Marketing Approval Restrictions, and Coping Strategies

Advanced Science, EarlyView.
This review comprehensively overviews attenuated bacteria‐based tumor therapy, highlighting key methodologies and recent progress. It examines strategies for enhancing safety, stabilizing efficacy, optimizing manufacturing, and navigating regulatory pathways.
Yucheng Liu, Junhong Yao, Jiaxin Deng, Minjie Zhou, Kaiyue Shen, Shishuo Sun, Xiaoge Gao, Qing Zhang, Haiheng Xu   +8 more
wiley   +1 more source