Enhancing conjugation from E. coli to Streptomyces coelicolor by incorporating traJ into mobilizable plasmids [PDF]
Streptomyces species are prolific producers of bioactive natural products, yet their genetic manipulation remains constrained by inefficient DNA delivery methods in many strains.
Angel Manteca Fernández +2 more
exaly +4 more sources
Dynamic inflammatory trajectories and 28-day mortality in patients in the intensive care unit: An exploratory observational study [PDF]
Background: Inflammatory dynamics profoundly influence outcomes in critically ill patients; however, the prognostic significance of early inflammatory trajectories remains unclear.
Xinyuan Ding +6 more
doaj +2 more sources
Identification of TRDV-TRAJ V domains in human and mouse T-cell receptor repertoires
Here, we describe the identification of two T-cell receptors (TRs) containing TRDV genes in their TRA chains, the first one in human and the second one in mouse.
Rienk Offringa +2 more
exaly +3 more sources
Utilization of lactate trajectory models for predicting acute kidney injury and mortality in patients with hyperlactatemia: insights across three independent cohorts [PDF]
This study aims to investigate the association between lactate trajectories and the risk of acute kidney injury (AKI) and hospital mortality in patients with hyperlactatemia.
Yipeng Fang +6 more
doaj +2 more sources
Association between renal mean perfusion pressure and prognosis in patients with sepsis-associated acute kidney injury: insights from the MIMIC IV database [PDF]
Objective To investigate the association between renal mean perfusion pressure (MPP) and prognosis in sepsis-associated acute kidney injury (SA-AKI).Methods Data were extracted from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database ...
Yipeng Fang +9 more
doaj +2 more sources
Objectives: Arterial hyperoxia is reportedly a risk factor for poor outcomes in patients with hemorrhagic brain injury (HBI). However, most previous studies have only evaluated the effects of hyperoxia using static oxygen partial pressure (PaO2) values ...
Guolong Cai +6 more
doaj +1 more source
A memorial piece in honour of Dr Lisa Lodwick (1988–2022), the founder and first Editor-in-Chief of TRAJ.
TRAJ Editorial Board
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Challenges in Open Data: A TRAJ Perspective
The editorial of the fifth issue of the Theoretical Roman Archaeology Journal focuses on the topic of open data. The editors consider both the challenges of using and disseminating open data within the field of Roman archaeology. We also reflect upon how
Francesca Mazzilli +1 more
doaj +2 more sources
Regulation of R1 Plasmid Transfer by H-NS, ArcA, TraJ, and DNA Sequence Elements
In conjugative elements such as integrating conjugative elements (ICEs) or conjugative plasmids (CPs) transcription of DNA transfer genes is a prerequisite for cells to become transfer competent, i.e., capable of delivering plasmid DNA via bacterial ...
Karin Bischof +6 more
doaj +1 more source
This article details a correction to the article. Webster, E. (2021). Innovation and Agency: To What Extent Did Cultural Appropriation Affect the Development of Jewellery in Britain During the 1st to 2nd Centuries AD?
Elizabeth Anne Grace Webster
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