Results 81 to 90 of about 2,702,596 (352)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

ECUMENISM AND INEQUALITY: The role of faith-based organizations for water advocacy in Brazil

open access: yesSur: International Journal on Human Rights, 2019
In the current context of intensifying the dichotomies related to the presence of religion in Brazilian politics, it is urgent to highlight the work of faith-based organizations for social justice.
Sheila Tanaka
doaj  

The Role of Cheese PDOs in the Resilience of Mountain Dairy Regions in Switzerland

open access: yesRevue de Géographie Alpine
Mountain dairy regions in Switzerland have experienced a trajectory of adaptation to changing framework conditions over the past thirty years. Through interviews with farmers who witnessed the past, we traced the agricultural history of two contrasting ...
Paul Donadieu de Lavit   +4 more
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Rôle des AOP fromagères dans la résilience des bassins laitiers de montagne en Suisse

open access: yesRevue de Géographie Alpine
Mountain dairy regions in Switzerland have experienced a trajectory of adaptation to changing framework conditions over the past thirty years. Through interviews with farmers who witnessed the past, we traced the agricultural history of two contrasting ...
Paul Donadieu de Lavit   +4 more
doaj   +1 more source

Word-level Symbolic Trajectory Evaluation

open access: yes, 2015
Symbolic trajectory evaluation (STE) is a model checking technique that has been successfully used to verify industrial designs. Existing implementations of STE, however, reason at the level of bits, allowing signals to take values in {0, 1, X}.
C-JH Seger   +8 more
core   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

open access: yesMolecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard   +12 more
wiley   +1 more source

Tracking the 6-DOF Flight Trajectory of Windborne Debris Using Stereophotogrammetry

open access: yesInfrastructures, 2019
Numerous post-windstorm investigations have reported that windborne debris can cause costly damage to the envelope of buildings in urban areas under strong winds (e.g., during hurricanes or tornados).
Chaman Lal Sabharwal, Yanlin Guo
doaj   +1 more source

Computing Similarity between a Pair of Trajectories [PDF]

open access: yes, 2013
With recent advances in sensing and tracking technology, trajectory data is becoming increasingly pervasive and analysis of trajectory data is becoming exceedingly important.
Agarwal, Pankaj K.   +3 more
core  

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

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