Results 61 to 70 of about 1,376,841 (287)
AlgorithmsVehicles conduct mandatory lane changes to merge into the open lanes in temporary highway work zones, and the merging characteristics have been widely studied over the past decades.
Yanli Jiao +4 more
doaj +1 more source
Sequential pattern mining from trajectory data [PDF]
Proceedings of the 17th International Database Engineering & Applications Symposium on - IDEAS '13, 2013 In this paper, we study the problem of mining for frequent trajectories, which is crucial in many application scenarios, such as vehicle traffic management, hand-off in cellular networks, supply chain management. We approach this problem as that of mining for frequent sequential patterns.
Masciari E, Shi Gao, Carlo Zaniolo
openaire +6 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck +12 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Variable-Based Spatiotemporal Trajectory Data Visualization Illustrated
IEEE Access, 2019 As a frontier research topic in the field of scientific visualization, trajectory data visualization extracts valuable patterns and knowledge from trajectory data for decision support via spatiotemporal trajectory visualization techniques. We propose the
Jing He +4 more
doaj +1 more source
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
A Novel Framework for Online Amnesic Trajectory Compression in Resource-constrained Environments
, 2016 State-of-the-art trajectory compression methods usually involve high space-time complexity or yield unsatisfactory compression rates, leading to rapid exhaustion of memory, computation, storage and energy resources. Their ability is commonly limited when
Jurdak, Raja +6 more
core +1 more source