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An overview of tramadol and its usage in pain management and future perspective
Biomedicine and Pharmacotherapy, 2019 Shalini Bajaj, Maushmi S Kumar
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Trends in Tramadol: Pharmacology, Metabolism, and Misuse
Anesthesia and Analgesia, 2017Karen Miotto, Mohamed A Khalil
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Drugs, 2003
The orally administered fixed combination tablet of tramadol (centrally-acting opiate) plus paracetamol (acetaminophen; nonopiate, nonsalicylate analgesic) [37.5/325 mg] provides effective analgesia in patients with moderate to severe acute pain and those with chronic painful conditions characterised by intermittent exacerbations of pain.
Karen, McClellan, Lesley J, Scott
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The orally administered fixed combination tablet of tramadol (centrally-acting opiate) plus paracetamol (acetaminophen; nonopiate, nonsalicylate analgesic) [37.5/325 mg] provides effective analgesia in patients with moderate to severe acute pain and those with chronic painful conditions characterised by intermittent exacerbations of pain.
Karen, McClellan, Lesley J, Scott
openaire +2 more sources
Current Opinion in Anaesthesiology, 2000
Tramadol is a unique analgesic offering moderate, dose-related pain relief through its action at multiple sites. In contrast to pure opioid agonists, it has a low risk of respiratory depression, tolerance and dependence. Troublesome side-effects have been reported, but tramadol has been established as an adjunct to non-steroidal anti-inflammatory drugs
P J, le Roux, J F, Coetzee
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Tramadol is a unique analgesic offering moderate, dose-related pain relief through its action at multiple sites. In contrast to pure opioid agonists, it has a low risk of respiratory depression, tolerance and dependence. Troublesome side-effects have been reported, but tramadol has been established as an adjunct to non-steroidal anti-inflammatory drugs
P J, le Roux, J F, Coetzee
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Tramadol use and public health consequences in Iran: a systematic review and meta-analysis.
Addiction, 2020BACKGROUND AND AIMS Misuse of tramadol, an opioid prescription analgesic, is known as a public health challenge globally. We aimed to systematically review studies on the prevalence of non-prescribed use, regular tramadol use and dependence, tramadol ...
Yasna Rostam-Abadi +7 more
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Microscopy and Microanalysis, 2020
Tramadol is a centrally acting analgesic drug, used for the management of moderate to severe pain in a variety of diseases. The long-term use of tramadol can induce endocrinopathy.
A. Shalaby +3 more
semanticscholar +1 more source
Tramadol is a centrally acting analgesic drug, used for the management of moderate to severe pain in a variety of diseases. The long-term use of tramadol can induce endocrinopathy.
A. Shalaby +3 more
semanticscholar +1 more source
ADME and toxicity considerations for tramadol: from basic research to clinical implications
Expert Opinion on Drug Metabolism & Toxicology, 2020Introduction Tramadol is widely being used in chronic pain management for improving patients’ life quality and reducing trauma. Although it is listed in several medicinal guidelines, its use is controversial because of the conflicting results obtained in
Mohsen Doostmohammadi, H. Rahimi
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Discovery and development of tramadol for the treatment of pain
Expert Opinion on Drug Discovery, 2017Juan-Antonio Mico, Esther M Berrocoso
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The effect of tramadol on blood glucose concentrations: a systematic review
Expert Review of Clinical Pharmacology, 2020Introduction Studies comprehensively summarizing the impact of tramadol use on glucose homeostasis are very sparse. Thus, the present study was performed to collect and summarize the latest information about this issue in a systematic way.
S. Nakhaee +6 more
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