Results 121 to 130 of about 5,120,986 (304)

Before the Burn: Predicting Endometrial Ablation Failure

Australian and New Zealand Journal of Obstetrics and Gynaecology, EarlyView.
ABSTRACT Background While endometrial ablation (EA) offers a minimally invasive alternative to a hysterectomy for women suffering from abnormal uterine bleeding (AUB), clinicians currently lack reliable predictive tools to identify which patients will experience treatment failure, leaving both providers and patients to make treatment decisions with ...
Anne Woolfield, Jessica Phillips, Ian Hughes, Kristen Jones, Rhys Harris, Sally Byford, Graeme Walker   +6 more
wiley   +1 more source

A systematic review and meta-analysis of systematic and topical tranexamic acid administration in aesthetic plastic surgery

Perioperative Medicine
Introduction Tranexamic acid has been widely used in plastic surgery. However, its efficacy has yet to be fully established. This meta-analysis aimed to determine its effectiveness in aesthetic plastic surgery.
Jerzy Kolasiński, Tomasz Reysner, Małgorzata Kolenda, Szymon Kołacz, Małgorzata Domagalska   +4 more
doaj   +1 more source

Efficacy and Safety of Tranexamic Acid in Melasma: A Meta-analysis and Systematic Review

Acta Dermato-Venereologica, 2017
Tranexamic acid is a novel treatment option for melasma; however, there is no consensus on its use. This systematic review searched major databases for relevant publications to March 2016. Eleven studies with 667 participants were included.
Hyun Jung Kim, Seok Hoon Moon, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim   +4 more
doaj   +1 more source

Effects of tranexamic acid on platelet function and thrombin generation (ETAPlaT): WOMAN trial sub-study. [PDF]

, 2016
Background. Postpartum haemorrhage (PPH) is a leading cause of maternal death. Tranexamic acid (TXA) has the potential to reduce bleeding and a large randomized placebo controlled trial of its effect in women with PPH (The WOMAN trial) is underway.
Beaumont, Danielle, Cenameri, Saimir, Dallaku, Kastriot, Delius, Maria, Edwards, Phil, Gliozheni, Orion, Mansmann, Ulrich, Roberts, Ian, Shakur, Haleema, Siegmund, Braun, Tasha, Ilir   +10 more
core   +2 more sources

Effect of peri‐operative pharmacological interventions on postoperative delirium in patients having cardiac surgery: a systematic review and Bayesian network meta‐analysis

Anaesthesia, EarlyView.
Summary Introduction Postoperative delirium is a common complication following cardiac surgery. Despite its known impact on patient outcomes, effective preventative strategies remain elusive. We aimed to perform a comprehensive Bayesian network meta‐analysis of randomised controlled trials assessing the effect of pharmacological interventions on the ...
Ivo Queiroz, Lucas M. Barbosa, Mariano Gallo Ruelas, Beatriz Araújo, Maria L. R. Defante, Arthur H. Tavares, Cynthia Florencio de Mesquita, Tulio Pimentel, Beatriz Ximenes Mendes, Iuri Ferreira Felix, André Rivera, Rafael Oliva Morgado Ferreira, Helen M. de Oliveira, Bruno B. Righetto, Nathan J. Smischney, Guangyu Tong, Daqing Ma   +16 more
wiley   +1 more source

Uptake of orally administered tranexamic acid in women during active labor: A pilot intervention study on prophylactic treatment of postpartum hemorrhage

Acta Obstetricia et Gynecologica Scandinavica
Introduction Postpartum hemorrhage is the leading cause of maternal mortality worldwide. Several studies have confirmed that tranexamic acid is effective in treating postpartum hemorrhage once started, but its prophylactic effect is under debate.
Gita Strindfors, Pelle G. Lindqvist, Margit Endler   +2 more
doaj   +1 more source

Tranexamic acid decreases rodent hemorrhagic shock-induced inflammation with mixed end-organ effects.

PLoS ONE, 2018
Beyond its anti-fibrinolytic mechanism, tranexamic acid has been suggested to have anti-inflammatory properties which may contribute to the survival benefit it provides to trauma patients.
Patrick F Walker, Anthony D Foster, Philip A Rothberg, Thomas A Davis, Matthew J Bradley   +4 more
doaj   +1 more source

The use of fibrinogen concentrate for the management of trauma-related bleeding. A systematic review and meta-analysis [PDF]

, 2017
Haemorrhage following injury is associated with significant morbidity and mortality. The role of fibrinogen concentrate in trauma-induced coagulopathy has been the object of intense research in the last 10 years and has been systematically analysed in ...
Franchini, Massimo, Liumbruno, Giancarlo M., Marano, Giuseppe, Marietta, Marco, Mengoli, Carlo, Pupella, Simonetta, Vaglio, Stefania   +6 more
core   +1 more source

Nebulized tranexamic acid for recurring hemoptysis in critically ill patients: case series [PDF]

, 2020
Fatimah Alabdrabalnabi, Mohammed Alshahrani, Nadia Ismail   +2 more
openalex   +1 more source

Establishment and Validation of a C57BL/6J Mouse Model for Melasma

Cell Proliferation, EarlyView.
A melasma‐like mouse model was established in C57BL/6J mice using a combination of UVB irradiation, progesterone administration, and chronic psychological stress. This model replicates key clinical features and biomarker alterations observed in human melasma. Importantly, it is fundamentally distinct from UV‐induced post‐inflammatory hyperpigmentation (
Wenzhu Wang, Xiaojie Sun, Yunyao Liu, Yin Yang, Hedan Yang, Xiaoli Zhang, Xiuzhen Li, Haoxiang Xu, Xu Chen, Tong Lin   +9 more
wiley   +1 more source