Results 131 to 140 of about 5,067,781 (348)
Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary IntraCerebral Haemorrhage’ (TICH-2) trial [PDF]
, 2017 Rationale Aside from blood pressure lowering, treatment options for intracerebral haemorrhage remain limited and a proportion of patients will undergo early haematoma expansion with resultant significant morbidity and mortality. Tranexamic acid (TXA),
CJ Dunn +16 more
core +3 more sources
Establishment and Validation of a C57BL/6J Mouse Model for Melasma
Cell Proliferation, EarlyView.A melasma‐like mouse model was established in C57BL/6J mice using a combination of UVB irradiation, progesterone administration, and chronic psychological stress. This model replicates key clinical features and biomarker alterations observed in human melasma. Importantly, it is fundamentally distinct from UV‐induced post‐inflammatory hyperpigmentation (
Wenzhu Wang +9 more
wiley +1 more source
Clinically Significant Thromboembolic Disease in Adult Spinal Deformity Surgery: Incidence and Risk Factors in 737 Patients. [PDF]
, 2017 Study Design:Retrospective cohort study. Objectives:Describe the rate and risk factors for venous thromboembolic events (VTEs; defined as deep venous thrombosis [DVT] and/or pulmonary embolism [PE]) in adult spinal deformity (ASD) surgery.
Bess, Shay +14 more
core +1 more source
Status quo and future developments in the diagnosis and treatment of hereditary angioedema
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Hereditary angioedema (HAE) is a rare hereditary disease characterized by edema, which can be life‐threatening in case of swelling in the larynx. The most common form of HAE is caused by a mutation of the SERPING1 gene and is characterized by a deficiency (type I) or loss of function (type II) of the C1 inhibitor (C1‐INH), leading to excessive ...
Andreas Recke
wiley +1 more source
BMC Surgery, 2011 Background Degenerative spinal stenosis and instability requiring multilevel spine surgery has been associated with large blood losses. Factors that affect perioperative blood loss include time of surgery, surgical procedure, patient height, combined ...
Endres Stefan, Heinz Martin, Wilke Axel
doaj +1 more source
تاثير دوز پروفيلاکتيک ترانکساميک اسيد در ميزان خونريزی در جراحيهای فک تحتانی: مطالعه کارآزمايی بالينی تصادفی دوسو کور [PDF]
, 2015 زمينه و هدف: ترانکساميک اسيد به‌منظور کاهش خونريزی و نياز به ترانسفوزيون در بسياری از جراحی‌ها به‌کار برده شده‌است. با توجه به اينکه جراحی‌های تروماتيک فک تحتانی می‌توانند با خونريزی مهمی همراه باشند که وضعيت فيلد جراحی را برای انجام جراحی ترميمی مشکل ...
ارقند, سکینه +5 more
core
European Journal of Haematology, EarlyView.ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman +10 more
wiley +1 more source
Применение транексамовой кислоты при эндопротезировании крупных суставов [PDF]
, 2013 КРОВОПОТЕРЯ ХИРУРГИЧЕСКАЯСУСТАВЫТРАНЕКСАМОВАЯ КИСЛОТА ...
Борисов, Д. Б. +1 more
core
European Journal of Haematology, EarlyView.ABSTRACT Objectives To evaluate the real‐world effectiveness of octocog alfa (BAY 81‐8973; Kovaltry) in people with haemophilia A (PwHA), including under‐represented subgroups. Methods We retrospectively analysed the American Thrombosis and Hemostasis Network (ATHN) dataset to identify the characteristics, treatment/clinical histories and annualised ...
Martin Chandler +4 more
wiley +1 more source