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Reactions Weekly, 2017 A new study has reported on the benefits of tranexamic acid in elective surgery. George Winter explores how it could also be a solution to the inequalities in global health
George F Winter
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Reactions Weekly, 2020
ABSTRACT A drug is defined in physiology as being a substance that exerts an effect on the body once it has been ingested or otherwise introduced. Drugs are administered in many forms, which include (but are not limited to) a variety of oral and topical preparations.
Lauren I. Yorozuya, Janiene D. Luke
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ABSTRACT A drug is defined in physiology as being a substance that exerts an effect on the body once it has been ingested or otherwise introduced. Drugs are administered in many forms, which include (but are not limited to) a variety of oral and topical preparations.
Lauren I. Yorozuya, Janiene D. Luke
+4 more sources
The Lancet, 2011
The CRASH-2 trial (July 3, p 23) showed reduced trauma mortality through the simple and cheap inter vention of tranexamic acid, placing it into a growing list of options for managing the acute coagulopathy of trauma. This list includes fresh frozen plasma, cryoprecipitate, platelets, fi brinogen, thrombin, prothrombin complexes, recombinant factor VIIa,
Russell L, Gruen, Biswadev, Mitra
openaire +2 more sources
The CRASH-2 trial (July 3, p 23) showed reduced trauma mortality through the simple and cheap inter vention of tranexamic acid, placing it into a growing list of options for managing the acute coagulopathy of trauma. This list includes fresh frozen plasma, cryoprecipitate, platelets, fi brinogen, thrombin, prothrombin complexes, recombinant factor VIIa,
Russell L, Gruen, Biswadev, Mitra
openaire +2 more sources
Annals of Pharmacotherapy, 1996
Tranexamic acid has the potential to be a pharmacologic adjunct for the prophylaxis of hemorrhagic complications occurring in the oncology population. The studies and cases reviewed here suggest that tranexamic acid administration may be a therapeutic option for bleeding prophylaxis in APL where enhanced fibrinolysis accompanies the disease state ...
A H, Seto, D S, Dunlap
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Tranexamic acid has the potential to be a pharmacologic adjunct for the prophylaxis of hemorrhagic complications occurring in the oncology population. The studies and cases reviewed here suggest that tranexamic acid administration may be a therapeutic option for bleeding prophylaxis in APL where enhanced fibrinolysis accompanies the disease state ...
A H, Seto, D S, Dunlap
openaire +2 more sources
Tranexamic Acid for Postpartum Bleeding
Obstetric Anesthesia Digest, 2011The randomized controlled trial of the effect of tranexamic acid (TXA) on blood loss during and after cesarean delivery reported by Movafegh et al. [1] in this issue of IJGO is clinically important for two reasons. First, because hemorrhage is a serious complication of cesarean delivery and their data show that bleeding can be reduced by TXA ...
Ian, Roberts, Katharine, Ker
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Annals of Emergency Medicine
A Joint Position Statement and Resource Document of NAEMSP, ACEP, and ACS-COT Prehospital use of tranexamic acid (TXA) has grown substantially over the past decade despite contradictory evidence supporting its widespread use. Since the previous guidance document on the prehospital use of TXA for injured patients was published by the National ...
Whitney J, Barrett +7 more
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A Joint Position Statement and Resource Document of NAEMSP, ACEP, and ACS-COT Prehospital use of tranexamic acid (TXA) has grown substantially over the past decade despite contradictory evidence supporting its widespread use. Since the previous guidance document on the prehospital use of TXA for injured patients was published by the National ...
Whitney J, Barrett +7 more
openaire +2 more sources
Tranexamic acid for post-partum haemorrhage: What, who and when [PDF]
Best Practice and Research in Clinical Obstetrics and Gynaecology, 2019 Tranexamic acid reduces bleeding by inhibiting the breakdown of blood clots. It is cost-effective and heat-stable with a long shelf life. In the WOMAN trial, tranexamic acid reduced deaths due to bleeding with no increase in thromboembolic events.
Amy Brenner +2 more
exaly +2 more sources