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Tranexamic Acid in Trauma Patients
2015Tranexamic acid is lysine-like drug that prevents the dissolution of the fibrin clot. It is associated with a significant reduction of bleeding, need of transfusion and mortality in several surgeries, such as cardiac or major orthopedic surgery.
Silvia Grossi +2 more
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1977
Tranexamic acid is the trans-isomer of 4-aminomethylcyclohexane carboxylic acid. The initial investigations were made using a preparation containing a mixture of isomers, but it was subsequently found (Melander et al. 1964; Okamoto et al., 1964) that only the trans-isomer is antifibrinolytically active.
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Tranexamic acid is the trans-isomer of 4-aminomethylcyclohexane carboxylic acid. The initial investigations were made using a preparation containing a mixture of isomers, but it was subsequently found (Melander et al. 1964; Okamoto et al., 1964) that only the trans-isomer is antifibrinolytically active.
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Perspectives on tranexamic acid in surgery
ANZ Journal of Surgery, 2020Kate L. King +3 more
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Tranexamic acid in emergency care
European Journal of Emergency Medicine, 2020openaire +3 more sources
Tranexamic acid and inflammation in trauma
ANZ Journal of Surgery, 2020Gabrielle D. Briggs +2 more
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2018
This chapter discusses papers by the CRASH-2 trial collaborators on tranexamic acid including the design of the studies (outcome measures, results, conclusions, and a critique).
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This chapter discusses papers by the CRASH-2 trial collaborators on tranexamic acid including the design of the studies (outcome measures, results, conclusions, and a critique).
openaire +1 more source