Results 121 to 130 of about 3,521 (321)

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

open access: yesChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz   +10 more
wiley   +1 more source

Child's Temperament as Risk Factor for Preoperative Anxiety—A Secondary Analysis of the ALPAKA Trial

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Preoperative anxiety is common in young children and may impair cooperation during anesthesia induction. Some temperament traits have been associated with higher anxiety levels in the preoperative phase. While midazolam is widely used for anxiolysis, individual responses vary and may be influenced by underlying psychological ...
Thorben Jacobi   +6 more
wiley   +1 more source

Efficacy and Safety of Dexmedetomidine‐Esketamine Versus Dexmedetomidine Alone as Premedication for Pediatric Anesthesia Induction: A Systematic Review, Meta‐Analysis, and Trial Sequential Analysis

open access: yesPediatric Anesthesia, EarlyView.
ABSTRACT Background Emergence delirium (ED) is a common complication in pediatric anesthesia. Although intranasal dexmedetomidine (DEX) is widely used, its application is constrained by a slow onset, residual risk of ED in some patients, and risks such as bradycardia and hypotension.
Munder Lateiresh   +5 more
wiley   +1 more source

What does coexistence mean? Insight from place‐based trajectories of pastoralists and bears encounters in the Pyrenees

open access: yesPeople and Nature, EarlyView.
Abstract The recovery of large carnivores in Europe raises issues related to sharing landscape with humans. Beyond technical solutions, it is widely recognized that social factors also contribute to shaping coexistence. In this context, scholars increasingly stress the need to adopt place‐based approaches by analysing how humans and wildlife interact ...
Alice Ouvrier   +7 more
wiley   +1 more source

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