Results 21 to 30 of about 3,521 (321)

Poly(lactic‐co‐glycolic acid) Nanoparticles for IL‐12 Self‐Amplifying RNA Delivery in Glioblastoma Models

open access: yesAdvanced Functional Materials, EarlyView.
xxxx. ABSTRACT Glioblastoma (GBM) remains one of the most lethal brain cancers, with median survival rarely exceeding 15 months after diagnosis. Interleukin‐12 (IL‐12) is a potent immunostimulatory cytokine capable of reshaping the tumor microenvironment (TME), yet its clinical translation is hindered by systemic toxicity and short half‐life. RNA‐based
Fatima Hameedat   +11 more
wiley   +1 more source

Contemporary management of pain in cirrhosis: Toward precision therapy for pain

open access: yesHepatology, EarlyView., 2022
Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman   +4 more
wiley   +1 more source

Formulation and quality control of a poly herbal tranquilizer syrup [PDF]

open access: yesResearch Journal of Pharmacognosy, 2017
Background and objectives: Herbal drugs are rapidly becoming popular in recent years as alternative therapies. Numerous poly herbal formulations, which are combinations of different herbal materials/extracts are being used for prevention or treatment of ...
doaj  

Toxicological profile of new biologically active substances – lithium and magnesium tartrategermanates

open access: yesJournal of V. N. Karazin Kharkiv National University: Series Medicine
Background. One of the most promising ways for development of new potential medical agents is to combine metal ions with bioligands that are derivatives of natural metabolites, in particular organic acids, which may be accompanied by an increase in the ...
К.F. Shemonayeva   +4 more
doaj   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

open access: yesAdvanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni   +15 more
wiley   +1 more source

Nurses\u27 Alumnae Association Bulletin, May 1957 [PDF]

open access: yes, 1957
Alumnae Notes Committee Reports Digest of Alumnae Meetings Graduation Awards - 1956 Letter from Hong Kong Leukemia Marriages Necrology New Arrivals Physical Advances at Jefferson President\u27s Message School of Nursing Report Two Year Programs in ...
Chan, Gertrude   +9 more
core   +1 more source

Autoimmune diabetes recurrence should be routinely monitored after pancreas transplantation [PDF]

open access: yes, 2014
Autoimmune type 1 diabetes recurrence in pancreas grafts was first described 30 years ago, but it is not yet completely understood. In fact, the number of transplants affected and possibly lost due to this disease may be falsely low.
Martins, L.
core   +1 more source

3D‐Printed Titanium Implants with Bioactive Peptide‐Polysaccharide Scaffolds for Personalized Bone Reconstruction

open access: yesAdvanced Healthcare Materials, EarlyView.
Porous 3D‐printed titanium implants are made bioactive by integration with a supramolecular peptide‐hyaluronic acid nanofibrillar scaffold, without the addition of exogenous cells or growth factors. Uniform filling of the implant architecture promotes vascularized, spatially homogeneous bone regeneration, significantly enhancing osteogenesis throughout
Noam Rattner   +8 more
wiley   +1 more source

Volume Five Subject Index [PDF]

open access: yes, 1969
Subject index for MCV/Q, Medical College of Virginia Quarterly, Volume ...

core   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

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