Results 71 to 80 of about 3,280,876 (283)

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System

ChemistryOpen, EarlyView.
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Meher Afroz, Rubel Hasan, Mst Muslima Khatun, Mokammel Hossain Tito, Md Shadin, Ranjit Chakma, Mohammed Asiri, Faisal H. Altemani, Abdullah H. Altemani, Md Shimul Bhuia, Muhammad Torequl Islam   +10 more
wiley   +1 more source

Religion and Regulatory Variance: Halal Regimes as Islamic Public Administration

Public Administration and Development, EarlyView.
ABSTRACT One quarter of humanity are Muslims, for whom halal food is an everyday consideration. The global food system has made assessing food products nearly impossible for consumers, requiring elaborate regulatory regimes. This article analyzes halal regulation as a notable example of Islamic public administration (IPA), as an application of ...
Logan Cochrane, Leslie A. Pal, Ibtisam B. Ajour   +2 more
wiley   +1 more source

Epidemiology, Morbidity and Mortality Associated With Anesthesia in Early Life: A Subgroup Analysis of the German NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) Cohort

Pediatric Anesthesia, EarlyView.
ABSTRACT Background The NEonate and Children audiT of Anesthesia pRactice IN Europe (NECTARINE) study, led by the ESAIC Clinical Trials Network, collected prospective data on 5609 children up to 60 weeks postmenstrual age undergoing 6542 anesthetic procedures across 165 centers in 31 European countries (ESAIC_CTN_NECTARINE).
Claudia Neumann, Alina Schenk, Ehrenfried Schindler, Karin Becke‐Jakob, German Nectarine Group Collaborators   +4 more
wiley   +1 more source

What does coexistence mean? Insight from place‐based trajectories of pastoralists and bears encounters in the Pyrenees

People and Nature, EarlyView.
Abstract The recovery of large carnivores in Europe raises issues related to sharing landscape with humans. Beyond technical solutions, it is widely recognized that social factors also contribute to shaping coexistence. In this context, scholars increasingly stress the need to adopt place‐based approaches by analysing how humans and wildlife interact ...
Alice Ouvrier, Manon Culos, Sylvie Guillerme, Antoine Doré, Helene Figari, John D. C. Linnell, Pierre‐Yves Quenette, Ruppert Vimal   +7 more
wiley   +1 more source

Pharmacotherapy of psychiatric inpatients with mental and behavioral disorders caused by sedatives or hypnotics (F13): Results from an observational pharmacovigilance program between 2000 and 2017. [PDF]

Addict Sci Clin Pract
Pauwels P, Haack B, Toto S, Seifert J, Grohmann R, Heinze M, Zolk O, Proskynitopoulos PJ, Schneider M, Greiner T.   +9 more
europepmc   +1 more source

Crosslinked Gelatin‐Polycaprolactone Scaffolds: Balancing Biocompatibility and Inflammatory Response for Tissue Engineering Applications

Polymer Engineering &Science, EarlyView.
Crosslinked gelatin‐functionalized PCL scaffolds exhibited enhanced hydrophilicity, structural stability, and porous interactions. In vitro assays demonstrated improved osteoblast adhesion, viability, and proliferation without cytotoxicity, while in vivo evaluation showed no adverse inflammatory response, supporting their potential application in ...
Fernanda Ramírez‐Ruiz, Israel Núñez‐Tapia, Lucía Pérez‐Sánchez, María Cristina Piña‐Barba, Irving Sanchez‐Leal, Marco Antonio Alvarez‐Perez, Iriczalli Cruz‐Maya, Janeth Serrano‐Bello   +7 more
wiley   +1 more source

Antipsychotic drugs at 75: the past, present, and future of psychosis management. [PDF]

Br Med Bull
Lyman M, McCutcheon RA.
europepmc   +1 more source

Effect of Testosterone Therapy on Cytochrome P450 3A and P‐Glycoprotein Activities Using Midazolam and Digoxin as Probe Substrates Among Transgender Adults

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, EarlyView.
ABSTRACT Background Gender‐affirming testosterone therapy is one part of the standard of care for more than 1 million transgender adults in the United States. Testosterone therapy may influence the activities of drug‐metabolizing enzymes and transporters, but knowledge about its effect on the pharmacokinetics of other medications is limited.
Michiko Hunter, Rene Coig, Linda Risler, Kristen K. Patton, Radhika R. Narla, Dina N. Greene, Alson K. Burke, Elizabeth Micks, Mary F. Hebert, Lauren R. Cirrincione   +9 more
wiley   +1 more source

Parenteral medication for the management of acute severe behavioural disturbance (ASBD) in the emergency department. [PDF]

Cochrane Database Syst Rev
Bourke E, Klein K, Knott J, Craig SS, Tavender E, Babl FE.   +5 more
europepmc   +1 more source

Ashwagandha: Is It Safe? Part 1: A Regulatory Review

Phytotherapy Research, EarlyView.
ABSTRACT Over the last decade, ashwagandha (Withania somnifera (L.) Dunal, AS) has been brought under increasing scrutiny by EU regulators regarding its safety for the use in food supplements, culminating in a recent recommendation for an Article 8 procedure according to Regulation (EC) No. 1925/2006 in the European Union (EU).
T. Brendler, R. Al‐Mondhiry, L. Lang, R. Marles, M. Tallon, A. Raghu   +5 more
wiley   +1 more source