Results 151 to 160 of about 30,445 (234)

Aberrant Splicing as a Mechanism for Resistance to Cancer Therapies. [PDF]

Cancers (Basel)
Duzgun D, Oltean S.
europepmc   +1 more source

WAVY LEAF1, an Ortholog of Arabidopsis HEN1, Regulates Shoot Development by Maintaining MicroRNA and Trans-Acting Small Interfering RNA Accumulation in Rice1[C][W]

Plant Physiology, 2010
Masashi Abe, Takanori Yoshikawa, M. Nosaka, H. Sakakibara, Yutaka Sato, Y. Nagato, J. Itoh   +6 more
semanticscholar   +1 more source

M2c Macrophages Mediate YAP1 to Promote Vascularized Bone Regeneration in Distraction Osteogenesis

The FASEB Journal, Volume 39, Issue 15, 15 August 2025.
During the process of DO, macrophages undergo polarization into M2c. The heightened expression of YAP1 by M2c leads to the promotion of angiogenesis in HUVECs, osteogenesis in BMSCs, and consequently, the acceleration of new bone formation. ABSTRACT Distraction osteogenesis (DO) is an efficient approach to addressing craniofacial deformities and bone ...
Haifeng Liu, Kai Liu, Yinyv Shang, Jinzhi Wei, Shixi He, Cheng Ma, Tianfeng Xu, Nuo Zhou, Peiqi Zhu, Xuanping Huang   +9 more
wiley   +1 more source

Small Interfering RNAs as Critical Regulators of Plant Life Process: New Perspectives on Regulating the Transcriptomic Machinery. [PDF]

Int J Mol Sci
Puchta-Jasińska M, Bolc P, Pietrusińska-Radzio A, Motor A, Boczkowska M.   +4 more
europepmc   +1 more source

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, Volume 15, Issue 8, Page 1303-1318, August 2025.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source

The REDUCED LEAFLET Genes Encode Key Components of the trans-Acting Small Interfering RNA Pathway and Regulate Compound Leaf and Flower Development in Lotus japonicus1[W][OA]

Plant Physiology, 2009
Jun Yan, X. Cai, Jiang-hong Luo, Shusei Sato, Qunyi Jiang, Jun Yang, Xiangling Cao, Xiao-he Hu, S. Tabata, P. Gresshoff, D. Luo   +10 more
semanticscholar   +1 more source

RONIN/HCF1‐TFEB Axis Protects Against D‐Galactose‐Induced Cochlear Hair Cell Senescence Through Autophagy Activation

Advanced Science, Volume 12, Issue 29, August 7, 2025.
D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei, Yuhua Zhang, Wei Cao, Nan Cheng, Yun Xiao, Yongjun Zhu, Yan Xu, Lei Zhang, Lingna Guo, Jun Song, Su‐hua Sha, Buwei Shao, Fang Ma, Jingwen Yang, Zheng Ying, Zuhong He, Renjie Chai, Qiaojun Fang, Jianming Yang   +18 more
wiley   +1 more source

SFSWAP is a negative regulator of OGT intron detention and global pre-mRNA splicing. [PDF]

Elife
Govindan A, Conrad NK.
europepmc   +1 more source

Decoding regulatory programs underlying placode and dermal condensate cell fate commitment during hair follicle induction via single‐cell multi‐omics analysis

Animal Research and One Health, Volume 3, Issue 3, Page 297-315, August 2025.
The experimental framework of the study encompasses sample collection, single‐cell data analysis, and experimental validation. Abstract Understanding differences in chromatin state and changes in gene regulatory landscape of placode (Pc) and dermal condensate are crucial for decoding hair follicle (HF) morphogenesis programs.
Fang Li, Minghao Li, Tongtong Zhang, Menghua Sui, Hasan Khatib, Xin Wang   +5 more
wiley   +1 more source

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancer. [PDF]

Cell Rep
Xiang RR, Lee SA, Tyndall CF, Bhatia AR, Yin J, Singler C, Hauk BJ, Kipp MP, Takeda DY.   +8 more
europepmc   +1 more source