Results 171 to 180 of about 59,578 (250)

In Vitro Efficacy of PEI-Derived Lipopolymers in Silencing of Toxic Proteins in a Neuronal Model of Huntington's Disease. [PDF]

Pharmaceutics
Morales LC, Modi L, Abbasi Dezfouli S, Rajendran AP, Kc R, Kadam V, Sipione S, Uludağ H.   +7 more
europepmc   +1 more source

Ten‐Eleven Translocation Family Proteins: Structure, Biological Functions, Diseases, and Targeted Therapy

MedComm, Volume 6, Issue 7, July 2025.
TET family proteins play a critical role in DNA demethylation, and their mutations and dysregulation contribute to the onset of multiple diseases. With a deeper understanding of the molecular mechanisms of TET involvement in disease, drug therapy targeting TET proteins shows great potential, which provides insights into new therapeutic strategies ...
Junzhi Liang, Xinni Na, Lingbo Meng, Lixia He, Ting Shu, Yuanyuan Fang, Bowen Zhang, Zhongyu Zhao, Cuishan Guo, Tingting Li, Zhijing Na, Da Li, Xue Xiao   +12 more
wiley   +1 more source

Empowering plant epigenetics to breed resilience of crops: From nucleolar dominance to transgenerational epigenetic inheritance. [PDF]

Plant Genome
Chen ZJ.
europepmc   +1 more source

Small Nucleolar RNAs: Biological Functions and Diseases

MedComm, Volume 6, Issue 7, July 2025.
The majority of snoRNAs are derived from the intron region of genes, besides to intronic snoRNAs, some snoRNAs are transcribed as independent genes, often by Pol II or III, these snoRNAs are called intergenic snoRNAs. All of these play a role in the occurrence and progression of various diseases through multiple functions.
Yi Wang, Min Fu, Zaiyong Zheng, Jianguo Feng, Chunxiang Zhang   +4 more
wiley   +1 more source

Long non-coding RNAs direct the SWI/SNF complex to cell type-specific enhancers. [PDF]

Nat Commun
Oo JA, Warwick T, Pálfi K, Lam F, McNicoll F, Prieto-Garcia C, Günther S, Cao C, Zhou Y, Gavrilov AA, Razin SV, Cabrera-Orefice A, Wittig I, Pullamsetti SS, Kurian L, Gilsbach R, Schulz MH, Dikic I, Müller-McNicoll M, Brandes RP, Leisegang MS.   +20 more
europepmc   +1 more source

Faculty Opinions recommendation of Ancient trans-Acting siRNAs Confer Robustness and Sensitivity onto the Auxin Response.

, 2016
Elena M. Kramer
openalex   +1 more source

Endoplasmic Reticulum Stress in Cancer

MedComm, Volume 6, Issue 7, July 2025.
Persistent ER stress in tumors activates UPR sensors (IRE1α, PERK, ATF6), driving cancer proliferation, metastasis, immune evasion, and drug resistance. This review explores UPR‐mediated signaling crosstalk, angiogenesis, and therapeutic targeting to develop safer anticancer strategies.
Ruixin Zhou, Wenlong Wang, Baizhao Li, Zhu Li, Juan Huang, Xinying Li   +5 more
wiley   +1 more source

Manipulation of Chemistry and Biology with Visible Light Using Tetra‐ortho‐Substituted Azobenzenes and Azonium Ions

Angewandte Chemie, Volume 137, Issue 24, June 10, 2025.
Tetra‐ortho‐Azobenzenes (TOABs) in broad daylight: in recent years, TOAB photoswitches became indispensable tools for all‐visible‐light manipulation of chemistry, biology and materials. This review explores their unique photochemical properties, design and synthetic approaches, offering support in choosing a TOAB for a given application.
Francesca Cardano, Rosa Márquez García, Wiktor Szymanski   +2 more
wiley   +2 more sources

Classification of and detection techniques for RNAi-induced effects in GM plants. [PDF]

Front Plant Sci
Diaz C, Ayobahan SU, Simon S, Zühl L, Schiermeyer A, Eilebrecht E, Eilebrecht S.   +6 more
europepmc   +1 more source

Landscape transcriptomics as a tool for addressing global change effects across diverse species

Molecular Ecology Resources, Volume 25, Issue 5, July 2025.
Abstract Landscape transcriptomics is an emerging field studying how genome‐wide expression patterns reflect dynamic landscape‐scale environmental drivers, including habitat, weather, climate, and contaminants, and the subsequent effects on organismal function. This field is benefitting from advancing and increasingly accessible molecular technologies,
Jason Keagy, Chloe P. Drummond, Kadeem J. Gilbert, Christina M. Grozinger, Jill Hamilton, Heather M. Hines, Jesse Lasky, Cheryl A. Logan, Ruairidh Sawers, Tyler Wagner   +9 more
wiley   +1 more source