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Multiple virus resistance using artificial trans-acting siRNAs

Journal of Virological Methods, 2016
Plant TAS gene encoded trans-acting siRNAs (ta-siRNAs) regulate the expression of target mRNAs by guiding their cleavage at the sequence complementary region as microRNAs. Since one TAS transcript is cleaved into multiple ta-siRNAs in a phased manner, TAS genes may be engineered to express multiple artificial ta-siRNAs (ata-siRNAs) that target multiple
Lingyun, Chen   +6 more
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miRNAs in the biogenesis of trans-acting siRNAs in higher plants

Seminars in Cell & Developmental Biology, 2010
Multicellular eukaryotes utilize many complex small RNA mechanisms to regulate gene expression from DNA modifications to RNA stability. RNA interference also regulates exogenous gene expression by degrading invading pathogen RNAs or preventing expression of foreign DNA incorporated into the host genome.
Edwards, Allen, Miya D, Howell
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Faculty Opinions recommendation of Ancient trans-Acting siRNAs Confer Robustness and Sensitivity onto the Auxin Response.

open access: closedFaculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016
Elena M. Kramer
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Characterisation of differentially expressed trans-acting siRNA (tasiRNAs) facing stress conditions in melon

open access: closed, 2018
[ES] Los trans-acting siRNAs (ta-siRNAs) son una clase de pequeños RNAs (20 a 24 nts) reguladores descritos en plantas. Se producen a partir de regiones especí cas del genoma llamadas genes TAS. Los transcritos derivados de estos genes TAS son reconocidos y procesados por un miRNA y por una RNA polimerasa RNA dependiente 6 (RDR6) para ...
Cervera Seco, Luís Manuel
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