Results 41 to 50 of about 30,445 (234)

A novel function of RING finger protein 10 in transcriptional regulation of the myelin-associated glycoprotein gene and myelin formation in Schwann cells.

PLoS ONE, 2008
Myelin-associated glycoprotein (MAG) has been detected in Schwann cells prior to the onset of myelination, suggesting its functions in the initiation of myelination. However, transcriptional regulatory mechanisms of MAG remain to be elucidated.
Shinya Hoshikawa, Toru Ogata, Sayaka Fujiwara, Kozo Nakamura, Sakae Tanaka   +4 more
doaj   +1 more source

Characterization of unique small RNA populations from rice grain.

PLoS ONE, 2008
Small RNAs (approximately 20 to 24 nucleotides) function as naturally occurring molecules critical in developmental pathways in plants and animals. Here we analyze small RNA populations from mature rice grain and seedlings by pyrosequencing.
Sara E Heisel, Yuanji Zhang, Edwards Allen, Liang Guo, Tracey L Reynolds, Xiao Yang, David Kovalic, James K Roberts   +7 more
doaj   +1 more source

AAV production in stable packaging cells requires expression of adenovirus 22/33K protein to allow episomal amplification of integrated rep/cap genes

Scientific Reports, 2023
Efficient manufacture of recombinant adeno-associated virus (rAAV) vectors for gene therapy remains challenging. Packaging cell lines containing stable integration of the AAV rep/cap genes have been explored, however rAAV production needs to be induced ...
Weiheng Su, Leonard W. Seymour, Ryan Cawood   +2 more
doaj   +1 more source

Genome Editing and Protoplast Regeneration to Study Plant–Pathogen Interactions in the Model Plant Nicotiana benthamiana

Frontiers in Genome Editing, 2021
Biotic diseases cause substantial agricultural losses annually, spurring research into plant pathogens and strategies to mitigate them. Nicotiana benthamiana is a commonly used model plant for studying plant–pathogen interactions because it is host to ...
Chen-Tran Hsu, Wen-Chi Lee, Yu-Jung Cheng, Yu-Hsuan Yuan, Fu-Hui Wu, Choun-Sea Lin   +5 more
doaj   +1 more source

Discriminating Mutations of HC-Pro of Zucchini yellow mosaic virus with Differential Effects on Small RNA Pathways Involved in Viral Pathogenicity and Symptom Development

Molecular Plant-Microbe Interactions, 2010
Helper component-proteinase (HC-Pro), the gene-silencing suppressor of Potyvirus spp., interferes with microRNA (miRNA) and short-interfering RNA (siRNA) pathways. Our previous studies showed that three mutations of highly conserved amino acids of HC-Pro,
Hui-Wen Wu, Shih-Shun Lin, Kuan-Chun Chen, Shyi-Dong Yeh, Nam-Hai Chua   +4 more
doaj   +1 more source

Endogenous TasiRNAs mediate non-cell autonomous effects on gene regulation in Arabidopsis thaliana. [PDF]

PLoS ONE, 2009
BackgroundDifferent classes of small RNAs (sRNAs) refine the expression of numerous genes in higher eukaryotes by directing protein partners to complementary nucleic acids, where they mediate gene silencing.
Rebecca Schwab, Alexis Maizel, Virginia Ruiz-Ferrer, Damien Garcia, Martin Bayer, Martin Crespi, Olivier Voinnet, Robert A Martienssen   +7 more
doaj   +1 more source

Genome-wide profiling of miRNAs and other small non-coding RNAs in the Verticillium dahliae-inoculated cotton roots. [PDF]

PLoS ONE, 2012
MicroRNAs (miRNAs) and small interfering RNAs (siRNAs) are short (19-25 nucleotides) non-coding RNA molecules that have large-scale regulatory effects on development and stress responses in plants. Verticillium wilt is a vascular disease in plants caused
Zujun Yin, Yan Li, Xiulan Han, Fafu Shen
doaj   +1 more source

Genetic information from discordant sibling pairs points to ESRP2 as a candidate trans-acting regulator of the CF modifier gene SCNN1B

Scientific Reports, 2020
SCNN1B encodes the beta subunit of the epithelial sodium channel ENaC. Previously, we reported an association between SNP markers of SCNN1B gene and disease severity in cystic fibrosis-affected sibling pairs. We hypothesized that factors interacting with
T. Becker, A. Pich, S. Tamm, Silke Hedtfeld, M. Ibrahim, J. Altmüller, N. Dalibor, M. Toliat, S. Janciauskiene, B. Tümmler, F. Stanke   +10 more
semanticscholar   +1 more source

PDL1-dependent trans-acting siRNAs regulate lateral organ polarity development in rice

Journal of Integrative Agriculture
Yi Zhang, Jing You, Jun Tang, Wenwen Xiao, Mi Wei, Ruhui Wu, Jinyan Liu, Hanying Zong, Shuoyu Zhang, Jie Qiu, Huan Chen, Yinghua Ling, Fangming Zhao, Yunfeng Li, Guanghua He, Ting Zhang   +15 more
openalex   +2 more sources

Faculty Opinions recommendation of Ancient trans-Acting siRNAs Confer Robustness and Sensitivity onto the Auxin Response.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2016
Elena M. Kramer
openalex   +2 more sources