Results 201 to 210 of about 3,099,679 (281)

New Ru(III) NAMI/NAMI-A Analogue Complexes with Selective Anticancer Activity. [PDF]

J Med Chem
Estruch-Blasco M, Calderón-Montaño JM, Álvarez E, Sánchez-Coronilla A, López-Lázaro M, Pernia Leal M.   +5 more
europepmc   +1 more source

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Disruption of plant cell division by methoxychalcones and cinnamaldehyde: insights into their herbicidal mode of action. [PDF]

Sci Rep
Garrido RM, Ozanique PR, Regasini LO, Dayan FE, Kolb RM.   +4 more
europepmc   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

<i>Eriobotrya japonica</i> (Loquat) Leaf Extract: An Integral In Vitro and In Ovo Approach to Antimelanoma Potential and Safety. [PDF]

Int J Mol Sci
Cristea AM, Macaşoi IG, Haj Ali D, Jupâneanț RA, Coricovac DE, Dehelean CA, Tchiakpe-Antal DS, Dumitrașcu V, Jîjie AR, Lăcătuș M, Anton A.   +10 more
europepmc   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

<i>trans</i>-Translation inhibitors that kill <i>Mycobacterium tuberculosis</i> and pathogenic non-tuberculous mycobacteria also disrupt metal homeostasis. [PDF]

Microbiology (Reading)
Varshney A, Jia Z, Gebretsadik G, G-Dayanandan N, Bowlin TL, Butler MM, Baughn AD, Keiler KC.   +7 more
europepmc   +1 more source

Dynamic response and failure of truncated hemispherical shells subjected to trans-medium projectile impact: Experiments and numerical simulations

Defence Technology
Yiming Ma, Jian Wang, Kui Tang, Jinxiang Wang, Xulong Hao, Xu Wang, Hanxin Gong, Minhui Gu   +7 more
openaire   +1 more source

Generation and Enhancement of Persistent Nanoscale Magnetization in All‐Dielectric Metasurfaces by Optically Injected and Localized Free Carriers

Advanced Science, EarlyView.
Infrared metasurface‐guided waves (IR‐MGW) scattered by a time interface (TI) induced by rapid, localized free‐carrier generation can be efficiently rectified to generate strong, persistent magnetic fields. We develop a rigorous, theoretical model to study a time‐varying, dispersive medium and uncover the redistribution of the initial energy of the IR ...
Shivaksh Rawat, Samyobrata Mukherjee, Gennady Shvets   +2 more
wiley   +1 more source

Chronic inflammation-responsive hydrogel restores myeloid-T cell crosstalk to reinvigorate antitumor immunity against metastatic colorectal cancer. [PDF]

Bioact Mater
Li X, Fu W, Le H, Luo R, Li Y, Kou X, He T, Bai L, Xu Y, Cao J, Wang Y, Yu X, Mi P, Luo Z, Gong C.   +14 more
europepmc   +1 more source