Results 61 to 70 of about 3,811,879 (232)

Mechanical Distraction Engages a Neuro‐Immune Program to Drive Regenerative Soft‐Tissue Healing in Ilizarov Bone Transport

open access: yesAdvanced Science, EarlyView.
Ilizarov bone transport accelerates healing of soft‐tissue wounds through unclear mechanisms. In a rat model, sustained mechanical distraction elicits calcitonin gene‐related peptide (CGRP)‐dominant sensory reinnervation, creating a niche that shifts immune cells from inflammatory to repair‐promoting states and speeds re‐epithelialization.
Yueliang Zhu   +9 more
wiley   +1 more source

Computer simulation of a series and parallel hybrid electric vehicle [PDF]

open access: yes, 1998
Although the internal combustion engine (ICE) vehicle is the most popular vehicle type in the world it has serious problems relating to its exhaust emissions and the limitation of petroleum resource.
Lee, Wonhee
core  

Histone Lactylation Drives WNK1 Expression to Promote Esophageal Squamous Cell Carcinoma Progression Through Histone H3 Ser10 Phosphorylation

open access: yesAdvanced Science, EarlyView.
In brief. Yan et al. demonstrated that the excess lactate produced by the enhanced glycolysis pathway in esophageal cancer can lactylate H3K23, H3K23la can be enriched in the WNK1 promoter region to promote WNK1 expression, thereby increasing the phosphorylation of the p‐H3 Ser10 site, and p‐H3S10 can be enriched in the AKT1 promoter region to promote ...
Mingyang Yan   +12 more
wiley   +1 more source

From Atoms to Reactors: A Critical Review of a Decade of Machine Learning in Heterogeneous Catalysis (2017–2026)

open access: yesAngewandte Chemie, EarlyView.
Machine learning has digitalized heterogeneous catalysis from the top of the length scale downward: prediction at the atom and the material is now mature, yet the reactor and the process remain the open frontier. This critical review traces a decade of progress across the full catalytic value chain and asks where the next decade of impact must be won ...
Rafael Larraz, Avelino Corma
wiley   +2 more sources

A Novel Bioactive Component, Efoba, From Aged Garlic Targets CTSC to Suppress NET‐Driven Neuroinflammation and Ameliorate Secondary Brain Injury After Intracerebral Hemorrhage

open access: yesAdvanced Science, EarlyView.
Efoba, a novel bioactive component derived from aged garlic, confers neuroprotection against intracerebral hemorrhage. It acts on microglia to suppress CTSC release, inhibits NET‐mediated neural injury, and blocks pathological microglia‐neutrophil crosstalk. This study provides a highly promising lead compound for hemorrhagic‐stroke therapy.
Junjun Meng   +7 more
wiley   +1 more source

Research of Trans-Medium Strategy for Unmanned Aerial-Undersea Vehicles

open access: yes水下无人系统学报
Unmanned aerial-undersea vehicles(UAUVs), with broad application prospects in both military and civilian fields, have gradually become a research hotspot in the field of robotics in recent years. UAUVs were taken as the research object in this study, and the development status of the bionic, multirotor, fixed-wing, and hybrid UAUV prototypes were ...
Kun LIU   +6 more
openaire   +1 more source

Optimizing a vehicle trans-atmospheric motion using Pontryagin’s maximum principle

open access: yes, 2018
The task of optimizing trans-atmospheric motion of a flight vehicle in order to maximize its final velocity with prescribed finite values of the height and flight path angle is considered.
V. L. Balakin   +2 more
core   +1 more source

Intelligent Polymer Electrolytes for Next‐Generation Zinc‐Based Energy Storage Devices

open access: yesAdvanced Science, EarlyView.
Intelligent polymer electrolytes are organized into a three‐level hierarchy that advances zinc‐based energy storage from passive ion conduction toward active, adaptive, and intelligent operation. Molecular regulation of Zn+ coordination, water activity, desolvation, ion flux, and interfaces underpins adaptive self‐healing, anti‐freezing, adhesion, and ...
Sanath Kumar   +4 more
wiley   +1 more source

Packing timber during construction of line [picture] /

open access: yes, 1917
"The rose series W.13"; Commonwealth Railways logo with map of Australia --back of photo.; P1877. Postcard photograph of the construction of the Trans-Australian Railway showing camel teams carting packing ...
Trans-Australian Railway.
core  

A UBE3A‐UTX Proteostasis‐Epigenetic Axis Governs Hypothalamic Energy Homeostasis

open access: yesAdvanced Science, EarlyView.
Ubiquitin protein ligase E3A (UBE3A) regulates hypothalamic energy homeostasis and promotes degradation of the histone demethylase UTX (KDM6A). Neuronal UBE3A loss increases susceptibility to diet‐induced obesity and is accompanied by UTX accumulation, reduced histone H3 lysine 27 trimethylation, and altered endoplasmic reticulum stress‐responsive gene
Junekyoung Lee   +7 more
wiley   +1 more source

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