Results 41 to 50 of about 1,159,549 (323)

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Les modes alternatifs de résolution des conflits sous l’empire de l’ordonnance criminelle : la loi et la doctrine

open access: yesCriminocorpus
In the summer of 1670, the committee responsible for drafting the criminal ordinance – which would be promulgated a few weeks later – met for its final conference.
Stéphanie Blot-Maccagnan
doaj   +1 more source

Au-delà de l’intelligibilité mutuelle : l’activité collective comme transaction. Un apport du pragmatisme illustré par trois cas

open access: yesActivités, 2013
Interactions are at the core of major sociological approaches to work. Some lines of research have accounted for cooperative interactions which include incommensurate perspectives.
Alexandra Bidet   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

open access: yesFEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Penerapan Blockchain dengan Integrasi Smart Contract pada Sistem Crowdfunding

open access: yesJurnal RESTI (Rekayasa Sistem dan Teknologi Informasi), 2021
The existing crowdfunding platforms still operate using centralized system. While centralized system can operate well, it requires a third party intermediary in order to operate and thus does not completely provide data security and transparency of ...
Fiqar Aprialim   +2 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Analysis and algorithm of operating logistic expenses measuring of the universal logistic systems [PDF]

open access: yesMarketing i Menedžment Innovacij, 2014
The aim of the article. The aim of the article consists in creation of technology of the logistic operations adjusting of universal logistic system functioning that is made by structural categories of logistic operating expenses.
T.V. Shcholokova
doaj  

THE ECONOMIC SUBSTANCE OF ACCOUNTING FOR FINANCIAL INVESTMENT AND THE PROSPECT OF USING “BLOCKCHAIN” TO CONTROL INVESTMENT ACTIVITY IN UKRAINE

open access: yesСучасний стан наукових досліджень та технологій в промисловості, 2018
The subject matter of the research is the financial investment and the application of innovative technologies to improve accounting in the context of investment management as one of the most important components of economic development.
Alina Lytvynenko, Yevgen Dorokhov
doaj   +1 more source

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