Results 41 to 50 of about 1,159,549 (323)
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
In the summer of 1670, the committee responsible for drafting the criminal ordinance – which would be promulgated a few weeks later – met for its final conference.
Stéphanie Blot-Maccagnan
doaj +1 more source
Interactions are at the core of major sociological approaches to work. Some lines of research have accounted for cooperative interactions which include incommensurate perspectives.
Alexandra Bidet +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
Innovators' gains from incumbents' exit options in
Mahmut N. Özdemir, Jan van den Ende
openalex +1 more source
Penerapan Blockchain dengan Integrasi Smart Contract pada Sistem Crowdfunding
The existing crowdfunding platforms still operate using centralized system. While centralized system can operate well, it requires a third party intermediary in order to operate and thus does not completely provide data security and transparency of ...
Fiqar Aprialim +2 more
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Analysis and algorithm of operating logistic expenses measuring of the universal logistic systems [PDF]
The aim of the article. The aim of the article consists in creation of technology of the logistic operations adjusting of universal logistic system functioning that is made by structural categories of logistic operating expenses.
T.V. Shcholokova
doaj
The subject matter of the research is the financial investment and the application of innovative technologies to improve accounting in the context of investment management as one of the most important components of economic development.
Alina Lytvynenko, Yevgen Dorokhov
doaj +1 more source

