Results 41 to 50 of about 1,121,515 (271)
Pediatric Blood &Cancer, EarlyView.ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm +10 more
wiley +1 more source
A Discussion on Document Conceptualization
Proceedings from the Document Academy, 2016 The authors discuss two conceptual frameworks of documents and documentation: Lund's complementarity theory of documentation; and Gorichanaz and Latham's framework of document phenomenology.
Niels Lund +2 more
doaj +1 more source
How to Charge Lightning: The Economics of Bitcoin Transaction Channels
, 2022 Off-chain transaction channels represent one of the leading techniques to scale the transaction throughput in cryptocurrencies. However, the economic effect of transaction channels on the system has not been explored much until now.
Brânzei, Simina +2 more
core
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
CriminocorpusIn the summer of 1670, the committee responsible for drafting the criminal ordinance – which would be promulgated a few weeks later – met for its final conference.
Stéphanie Blot-Maccagnan
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Automatic Verification of Transactions on an Object-Oriented Database [PDF]
, 1997 In the context of the object-oriented data model, a compiletime approach is given that provides for a significant reduction of the amount of run-time transaction overhead due to integrity constraint checking.
Balsters, H., Spelt, D.
core +4 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Unlocking Blockchain Interconnectivity: Smart Contract-Driven Cross-Chain Communication
IEEE Access, 2023 In recent years, blockchain technology has gained significant attention for its potential in various domains. However, the lack of interoperability between different blockchain platforms poses a significant challenge in meeting the demands of the modern ...
Kirtirajsinh Zala +5 more
doaj +1 more source