Results 71 to 80 of about 1,121,515 (271)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Transactions in a Native Land

open access: yesRSA Journal, 1992
Erdrich is a metis Chippewa writer whose multivoiced semi-autobiographical fiction expresses the Indian mixed-bloods' complex mediation between the marginal world of the reservations and their urban surroundings.
Daniela Daniele
doaj   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Initial allocation of carbon emission permits in power systems

open access: yesJournal of Modern Power Systems and Clean Energy, 2017
Initial allocation modes and schemes are studied in this paper to provide guidelines for allocation of carbon emission permits in power system. We first introduce different allocation modes and the need to apply free allocation to assignability of ...
Tan Wang   +6 more
doaj   +1 more source

MANAGING TRANSACTION EXPOSURE [PDF]

open access: yes
In the period of crisis the volatility of foreign exchange is one of most importantelements to be consider in the risk management strategy at corporate level .The paper will focus onthe main types of foreign exchange exposure, the role of hedging in ...
Dalina Dumitrescu
core  

Optimal Investment with Transaction Costs and Stochastic Volatility [PDF]

open access: yes, 2014
Two major financial market complexities are transaction costs and uncertain volatility, and we analyze their joint impact on the problem of portfolio optimization.
Bichuch, Maxim, Sircar, Ronnie
core   +1 more source

Targeting p38α in cancer: challenges, opportunities, and emerging strategies

open access: yesMolecular Oncology, EarlyView.
p38α normally regulates cellular stress responses and homeostasis and suppresses malignant transformation. In cancer, however, p38α is co‐opted to drive context‐dependent proliferation and dissemination. p38α also supports key functions in cells of the tumor microenvironment, including fibroblasts, myeloid cells, and T lymphocytes.
Angel R. Nebreda
wiley   +1 more source

Endogenous Transaction Costs [PDF]

open access: yes
The paper proposes an alternative general equilibrium formulation of financial asset economies with transactions costs. Transaction costs emerge endogenously at equilibrium and reflect agents decisions of intermediating financial activities at the ...
Martins-da-Rocha, Victor Filipe   +1 more
core  

Pay One, Get Hundreds for Free: Reducing Cloud Costs through Shared Query Execution

open access: yes, 2018
Cloud-based data analysis is nowadays common practice because of the lower system management overhead as well as the pay-as-you-go pricing model. The pricing model, however, is not always suitable for query processing as heavy use results in high costs ...
Chen Chung-Min   +6 more
core   +1 more source

RaMBat: Accurate identification of medulloblastoma subtypes from diverse data sources with severe batch effects

open access: yesMolecular Oncology, EarlyView.
To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley   +1 more source

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