Results 41 to 50 of about 368,657 (289)

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

Harp: optimization algorithm for cross-domain distributed transactions

open access: yes大数据, 2023
The paradigm of near-data computing has driven banks and securities firms to build multiple data centers globally or nationally.In the traditional business model, transactions focused on accessing data within a single data center.With the changing ...
Qiyu ZHUANG   +3 more
doaj  

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

ASSESSMENT OF TRANSACTION PERFORMANCE UNDER DISTRIBUTED REAL TIME DATABASE SYSTEM

open access: yesElectrica, 2008
The objective of this paper is to forecast the performance of transaction under real time distributed system. A real time database system is a transaction processing system design to handle the workload within a deadline.
Sanasam Bimol   +3 more
doaj   +2 more sources

Payment Transaction Processing System Design on PT. Air Comm [PDF]

open access: yes, 1998
With the design of information systems at the administrative and financial administration. Air Comm, can help the management in managing the payment transaction data in a faster and more accurate calculation of the payment transaction can be trusted so ...
Irwan Bastian, SKom, MM   +1 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

EC-ElGamal and Genetic Algorithm-Based Enhancement for Lightweight Scalable Blockchain in IoT Domain

open access: yesIEEE Access, 2020
Security, data privacy and decentralization are significant challenges in the Internet of Things (IoT) domain. These challenges are inherited attribute of another emerging technology, Blockchain.
J. Guruprakash, Srinivas Koppu
doaj   +1 more source

Tree-Chain: A Fast Lightweight Consensus Algorithm for IoT Applications

open access: yes, 2020
Blockchain has received tremendous attention in non-monetary applications including the Internet of Things (IoT) due to its salient features including decentralization, security, auditability, and anonymity.
Dorri, Ali, Jurdak, Raja
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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