Results 201 to 210 of about 134,646 (295)

Regulating Enzyme Activity via Microaggregates Mediated by Phase Separation

open access: yesAdvanced Science, EarlyView.
An enzyme‐sequestration strategy for combating postoperative pancreatic fistula (POPF) is developed, employing a D‐peptide called DPMD to induce liquid–solid phase separation (LSPS) of pancreatic proteases. This LSPS‐driven microaggregate approach effectively isolates trypsin and chymotrypsin from their substrates, thereby reducing pancreatic fluid ...
Yang Wang   +7 more
wiley   +1 more source

Transaminase Activity in Sheep Rumen Content

open access: bronze, 1969
Hiroyuki Tsubota, Sadao HOSHINO
openalex   +1 more source

Lutetium‐Based Nanoprobes for Radiosensitization with Immune Microenvironment Remodeling and NIR‐II Fluorescence Imaging‐Guided Surgery in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
Enhancing radiosensitization, modulating the tumor immune microenvironment, and ensuring complete resection are crucial for colorectal cancer (CRC) treatment. This study presents a multifunctional NIR‐II fluorescent nanoprobe, RVLu@ICG, which enhances radiosensitization, remodels the tumor immune microenvironment, and enables precise image‐guided ...
Yongying Dang   +10 more
wiley   +1 more source

A Mesoporous Calcium Peroxide Nanocuboid with High Tumor Accumulation Across Biological Barriers for High Efficacy Tumor Therapy

open access: yesAdvanced Science, EarlyView.
The ferroheme (FH) and exceedingly small magnetic iron oxide nanoparticles (IO) loaded mesoporous calcium peroxide nanocuboid (MCPNC) with conjugation of hyaluronic acid (HA) possesses exceptional capability of tumor accumulation, and enhances therapeutic efficacy of tumors based on the mechanism of promoting a positive feedback loop of Fenton reaction
Qingdeng Fan   +17 more
wiley   +1 more source

FIB‐3 index as a novel age‐independent predictor of liver fibrosis and prognosis in hepatocellular carcinoma patients undergoing hepatectomy

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Fibrosis‐3 index (FIB‐3) can stratify the risk of the survival and the recurrence‐free survival. The FIB‐3 index is a reliable, age‐independent tool for assessing liver fibrosis and prognosis in HCC patients post‐hepatectomy. Its use may improve clinical outcomes and support personalized treatment strategies. Abstract Background Liver fibrosis is a key
Yuki Imaoka   +13 more
wiley   +1 more source

Nationwide Trends in Short‐Term Outcomes After Low Anterior Resection for Rectal Cancer: A Pre‐ and Post‐COVID‐19 Analysis From the Japanese National Clinical Database, 2018–2023

open access: yesAnnals of Gastroenterological Surgery, EarlyView.
Despite initial challenges, the healthcare system of Japan effectively managed rectal cancer surgeries during and after the COVID‐19 pandemic. Robotic surgery became more widely adopted, and complication rates improved, demonstrating resilience and adaptability in surgical care.
Ryo Seishima   +13 more
wiley   +1 more source

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