Results 31 to 40 of about 251,409 (391)

Immobilized Whole-Cell Transaminase Biocatalysts for Continuous-Flow Kinetic Resolution of Amines

open access: yesCatalysts, 2019
Immobilization of transaminases creates promising biocatalysts for production of chiral amines in batch or continuous-flow mode reactions. E. coli cells containing overexpressed transaminases of various selectivities and hollow silica microspheres as ...
Z. Molnár   +7 more
semanticscholar   +1 more source

Enhancing PLP-Binding Capacity of Class-III ω-Transaminase by Single Residue Substitution

open access: yesFrontiers in Bioengineering and Biotechnology, 2019
Transaminases are pyridoxal-5′-phosphate (PLP) binding enzymes, broadly studied for their potential industrial application. Their affinity for PLP has been related to their performance and operational stability and while significant differences in PLP ...
David Roura Padrosa   +7 more
doaj   +1 more source

A Puzzling Protein from Variovorax paradoxus Has a PLP Fold Type IV Transaminase Structure and Binds PLP without Catalytic Lysine

open access: yesCrystals, 2022
Effective biocatalysts for the synthesis of optically pure amines from keto precursors are highly required in organic synthesis. Transaminases are a large group of PLP-dependent enzymes, which can be utilized for production of chiral amines or amino ...
Konstantin M. Boyko   +6 more
doaj   +1 more source

Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]

open access: yes, 2010
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson   +41 more
core   +1 more source

Detoxification of Fumonisins by Three Novel Transaminases with Diverse Enzymatic Characteristics Coupled with Carboxylesterase

open access: yesFoods, 2023
Fumonisin (FB) is one of the most common mycotoxins contaminating feed and food, causing severe public health threat to human and animals worldwide.
Yue Wang   +8 more
doaj   +1 more source

Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]

open access: yes, 2017
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola   +3 more
core   +1 more source

Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts

open access: yes, 2017
Transaminases have attracted considerable interest in their use as biocatalysts for the synthesis of compounds containing chiral amine units, which are widespread within the pharmaceutical, agrochemical, and fine chemical industry. Recent developments in
Iustina Slabu   +3 more
semanticscholar   +1 more source

2-Pyrrolidinone and Succinimide as Clinical Screening Biomarkers for GABA-Transaminase Deficiency: Anti-seizure Medications Impact Accurate Diagnosis

open access: yesFrontiers in Neuroscience, 2019
Broad-scale untargeted biochemical phenotyping is a technology that supplements widely accepted assays, such as organic acid, amino acid, and acylcarnitine analyses typically utilized for the diagnosis of inborn errors of metabolism.
C. Bonvicini   +13 more
semanticscholar   +1 more source

Evidence of Phenylalanine Transaminase Activity in the Isoenzymes of Aspartate Transaminase

open access: yesJournal of Biological Chemistry, 1972
Abstract The transamination by pig mitochondrial and supernatant aspartate transaminase of aromatic amino acids was studied in order to determine if an analogy exists between these enzymes and a previously reported brain phenylalanine transaminase (George, H., and Gabay, S. (1968) Biochim. Biophys. Acta, 167, 555).
Elsie J. Shrawder   +1 more
openaire   +3 more sources

Efficacy of Heptral® in the treatment of hepatic toxicity induced by cytostatic chemotherapy

open access: yesОпухоли женской репродуктивной системы, 2014
The efficacy of Heptral® (ademethionine) was evaluated in the treatment of chemotherapy-induced hepatotoxicity in 19 patients with various malignancies.
A. V. Snegovoy, L. V. Manzyuk
doaj   +1 more source

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