Immobilized Whole-Cell Transaminase Biocatalysts for Continuous-Flow Kinetic Resolution of Amines
Immobilization of transaminases creates promising biocatalysts for production of chiral amines in batch or continuous-flow mode reactions. E. coli cells containing overexpressed transaminases of various selectivities and hollow silica microspheres as ...
Z. Molnár+7 more
semanticscholar +1 more source
Enhancing PLP-Binding Capacity of Class-III ω-Transaminase by Single Residue Substitution
Transaminases are pyridoxal-5′-phosphate (PLP) binding enzymes, broadly studied for their potential industrial application. Their affinity for PLP has been related to their performance and operational stability and while significant differences in PLP ...
David Roura Padrosa+7 more
doaj +1 more source
Effective biocatalysts for the synthesis of optically pure amines from keto precursors are highly required in organic synthesis. Transaminases are a large group of PLP-dependent enzymes, which can be utilized for production of chiral amines or amino ...
Konstantin M. Boyko+6 more
doaj +1 more source
Comparison of the prognostic value of tumour and patient related factors in patients undergoing potentially curative surgery for colon cancer [PDF]
<b>Aim</b>: To comprehensively compare the prognostic value of tumour and patient-related factors in patients undergoing curative surgery for colon cancer.
Benson+41 more
core +1 more source
Fumonisin (FB) is one of the most common mycotoxins contaminating feed and food, causing severe public health threat to human and animals worldwide.
Yue Wang+8 more
doaj +1 more source
Effects of Raw Ethanolic Seed Extract of Tetracarpidium conophorum on Heamatological and Histopathological Parameters in Swiss Albino Mice Infected with Plasmodium berghei [PDF]
Study was carried out to determine the heamatological and histopathological effects of raw ethanolic seed extract of Tetracarpidium conophorum in swiss albino mice infected with Plasmodium berghei (NK65).
D. A. Oloruntola+3 more
core +1 more source
Discovery, Engineering, and Synthetic Application of Transaminase Biocatalysts
Transaminases have attracted considerable interest in their use as biocatalysts for the synthesis of compounds containing chiral amine units, which are widespread within the pharmaceutical, agrochemical, and fine chemical industry. Recent developments in
Iustina Slabu+3 more
semanticscholar +1 more source
Broad-scale untargeted biochemical phenotyping is a technology that supplements widely accepted assays, such as organic acid, amino acid, and acylcarnitine analyses typically utilized for the diagnosis of inborn errors of metabolism.
C. Bonvicini+13 more
semanticscholar +1 more source
Evidence of Phenylalanine Transaminase Activity in the Isoenzymes of Aspartate Transaminase
Abstract The transamination by pig mitochondrial and supernatant aspartate transaminase of aromatic amino acids was studied in order to determine if an analogy exists between these enzymes and a previously reported brain phenylalanine transaminase (George, H., and Gabay, S. (1968) Biochim. Biophys. Acta, 167, 555).
Elsie J. Shrawder+1 more
openaire +3 more sources
Efficacy of Heptral® in the treatment of hepatic toxicity induced by cytostatic chemotherapy
The efficacy of Heptral® (ademethionine) was evaluated in the treatment of chemotherapy-induced hepatotoxicity in 19 patients with various malignancies.
A. V. Snegovoy, L. V. Manzyuk
doaj +1 more source