Results 91 to 100 of about 122,944 (342)

Structural and functional characterisation of a lytic transglycosylase and two ω-transaminases [PDF]

, 2015
This thesis describes the determination and analysis of 3D-structures of enzymes from two different enzyme classes, the lytic transglycosylase MltF from Pseudomonas aeruginosa and two ω-transaminases, an (R)-selective transaminase from an Arthrobacter ...
Reddem, Eswarreddy
core   +4 more sources

Association of serum transaminases with short- and long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention

BMC Cardiovascular Disorders, 2017
BackgroundAlanine transaminase (ALT) and aspartate aminotransferase (AST) are referred to as liver transaminases. Although used routinely in clinical practice for decades, their role as predictors of mortality has not been examined until recently.
Ming Gao, Yi Cheng, Yang Zheng, Weihua Zhang, Lin Wang, L. Qin   +5 more
semanticscholar   +1 more source

Role of Glutamine Transaminases in Nitrogen, Sulfur, Selenium, and 1-Carbon Metabolism

, 2014
Glutamine metabolism is largely controlled by two enzyme pathways: 1) Conversion of glutamine to glutamate catalyzed by glutaminases, followed by conversion of glutamate to α-ketoglutarate by a glutamate-linked aminotransferases (or by the action of ...
Dorai, Thambi, Hallen, andré, Jianyong Li, John Thomas Pinto, Li, Jianyong, Dorai, Bhuvaneswari, Krasnikov, Boris F, Arthur J. L. Cooper, Boris F. Krasnikov, Thambi Dorai, Pinto, John T, Bhuvaneswari Dorai, André Hallen, Cooper, Arthur J L   +13 more
core   +1 more source

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

Advanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang, Yi Song, Changkun Li, Yuanyuan Luo, Mingwei Shao, Feng Guo, Fangyi Wei, Xunjie Fan, Wenwen Guo, Fengmei Xu, Yanhong Sang, Dongming Zhang, Yanhong Zhou, Lianwei Wang, Zhiqiang Kang, Yingjun Yang, Chunhua Song, Yanxia Liu, Xiaojun Ma, Jiao Wang, Chong Li, Shengnan Ma, Lin Zhao, Zhi Qin, Guolan Xing, Qiubo Zhao, Jun Li, Shumin Song, Dan Zhao, Ting Huang, Qingzhu Wang, Yanyan Zhao, Guijun Qin   +32 more
wiley   +1 more source

Effect of Eight-Week Aquagymnastic Training on Liver Enzymes and Lipid Profile of Middle-Aged Women

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: Regarding the effect of exercise on liver enzymes and lipid profile and the results of previous studies confirming positive effects of land-based exercise, and emphasizing the benefits of aquagymnastic training, this study ...
Abdosaleh Zar, Seyed Ali Hosseini, Atieh Homaion   +2 more
doaj  

Seroprevalence and biochemical parameters among patients with Chikungunya in Adamaoua region, Cameroon: A cross‐sectional study

Public Health Challenges
Background Chikungunya virus (CHIKV) infection is a vector‐borne febrile illness endemic to Africa. In Cameroon, few studies have documented human exposure to CHIKV, especially in the Adamaoua region.
Lise Paule Djamko Toko, Borris Rosnay Galani Tietcheu, Ilyassa Dieudonné Tembar, Pascal Dieudonne Chuisseu Djamen, Nicolas Njintang Yanou   +4 more
doaj   +1 more source

[Elevated transaminases - what to do if everything was done?]

, 2009
Transaminases, gamma-GT and alcalic phosphatase are classically termed as liver enzymes, however they can be found in almost every organ. Elevated levels of the transaminases ALAT (alanin-aminotransferase) and ASAT (aspartat-aminotransferase) are signs ...
Dufour, Jean-François, Lepper, P M
core  

Transaminases increase: a manifestation of Duchenne’s muscular dystrophy [PDF]

, 2012
Commonly used in clinical practice, glutamic oxalacetic (GOT) and glutamic piruvic (GPT) transaminases are produced in various body tissues, including striated muscle, so their blood elevation is not due exclusively to liver disease.
Beytía, María de los Ángeles, Kleinsteuber, Karin, Avaria Benapres, María de los Ángeles, Alegría Quevedo, Sylvia, Rodillo, Eliana   +4 more
core  

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

Advanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du, Changyu Pi, Kai Hong, Le Gao, Xin Wu   +4 more
wiley   +1 more source

Membrane-immobilized transaminases for the synthesis of enantiopure amines

For the manufacture of enantiopure amines, greener synthesis processes are needed. Transaminases (TAs) are able to produce chiral amines with excellent enantioselectivity and in mild conditions, and can be immobilized to target stability, recoverability,
David, Roura Padrosa, Xuan Dieu Linh, Nguyen, Tom, Leyssens, Hippolyte, Meersseman Arango, Francesca, Paradisi, Damien, Debecker, Patricia, Luis   +6 more
core   +1 more source