Results 91 to 100 of about 10,864 (249)

Hyperpolarization of [1‐13C]Ketoisocaproate‐d2 by Reversible Exchange with Parahydrogen Enables Profiling of Branched‐Chain‐Amino‐Acid Metabolism in Cellulo and in Vivo

Advanced Science, EarlyView.
We report the fast generation of biocompatible solutions of highly 13C‐hyperpolarized (≈11%) partially‐deuterated ketoisocaproate within <6 min using spin‐lock‐induced crossing and reversible exchange with parahydrogen (SLIC‐SABRE). This enables rapid detection of branched‐chain‐amino‐acid transferase 1 (BCAT1) protein expression and investigation of ...
Stefan Petersen, Philipp R. Groß, Paul M. Schmidt, Henri de Maissin, Asitan Rittinger, Robert Willing, Adriana Sacristán‐Martín, Lisa Heß, Jule Koch, Sebastian Lucas, Maxim Zaitsev, Dominik von Elverfeldt, Martin Grashei, Franz Schilling, Jan‐Bernd Hövener, André F. Martins, Max von Delius, Thomas Reinheckel, Andreas B. Schmidt   +18 more
wiley   +1 more source

Monitoramento de eletrólitos, de marcadores de danos musculares e função renal em atletas de Futebol de Elite

Revista Brasileira de Nutrição Esportiva, 2018
O monitoramento de marcadores bioquímicos é necessário para conhecer o estado orgânico de atletas diante da rotina extenuante de treinamento e competição.
Bruna Krefta, Caroline Vechi, Flavia Gabriela Pinezi, Thais Regina Mezzomo   +3 more
doaj  

A Machine Vision‐Guided Microphysiological Platform With Automated Microfluidics Enables Longitudinal Biomarker Monitoring and Emulation of Translationally Relevant Exposure Scenarios

Advanced Science, EarlyView.
A pneumatically actuated multi‐tissue microphysiological system is integrated with AI‐based machine vision and automatic sampling and replenishment systems. The platform allows for the emulation of translationally relevant long‐term pharmacokinetic exposure scenarios for multiple weeks while enabling longitudinal monitoring of response biomarkers ...
Jibbe Keulen, Yi Zhong, Laura Dangel, Sonia Youhanna, Reza Zandi Shafagh, Jinhye Ryu, Domnica‐Gabriela Gurau, Mathias Haag, Thomas E. Mürdter, Yingxin Liang, Iro Beligiani, Nicole Ziegler, Sabine Willems, Nayere Taebnia, Wouter van der Wijngaart, Volker M. Lauschke   +15 more
wiley   +1 more source

Dietary licorice (Glycyrrhiza glabra) supplementation enhances growth, antioxidant defence, and modulates metabolic enzyme activity in Labeo rohita

Frontiers in Marine Science
This study aims to assess the impact of liquorice (Glycyrrhiza glabra) on the growth, immunity, digestive enzyme activity and metabolism of Labeo rohita.
Ravishekhar Kumar, Sarvendra Kumar, Showkat Ahmad Dar, Sagarika Swain, Ravi Shankar Kumar   +4 more
doaj   +1 more source

Ornithine Transaminase [PDF]

Nature, 1951
J H, QUASTEL, R, WITTY
openaire   +2 more sources

Fetomaternal outcome in cases of pregnancy with deranged transaminases

Objective: To evaluate the fetomaternal outcomes associated with abnormal transaminases in late pregnancy and to identify maternal factors predictive of adverse neonatal outcomes.
Abida Ashraf, Huma Ijaz, Amel Amjad Buttar, Assma Majeed, Amber Ijaz   +4 more
core   +1 more source

Bioengineered Exosome‐Loaded Immunomodulatory Bioadhesive Spray Reverses Liver Fibrosis and Metabolic Dysfunction That Triggers Beneficial Gut‐Liver Crosstalk in Chronic Fatty Liver Disease

Advanced Science, EarlyView.
Umbilical cord stem cell‐derived exosomes encapsulated in an immunomodulatory bioadhesive hydrogel spray enable localized therapy, sustained vesicle delivery, macrophage polarization, suppress systemic inflammation, and mitigate glucose and insulin homeostasis impairments in MAFLD.
Triya Saha, Ayushi Mairal, Shreya Mehrotra, Shiv K. Sarin, Ashok Kumar   +4 more
wiley   +1 more source

Dosages colorimétriques continus à haut débit pour les alpha-transaminases.

, 2017
International audienceTransaminases are efficient tools for the stereoselective conversion of prochiral ketones into valuable chiral amines. Notably, the diversity of naturally occurring α-transaminases offers access to a wide range of l- and d-α-amino ...
de Berardinis, Véronique, Heuson, Egon, Gefflaut, Thierry, Charmantray, Franck, Petit, Jean-Louis   +4 more
core   +3 more sources

Elevated Transaminases: Does It Always Warrant a Liver Biopsy? Lessons Learned From Pompe Disease

JIMD Reports
Pompe disease (PD) is an autosomal recessive disorder caused by pathogenic variants in GAA, resulting in acid alpha‐glucosidase (GAA) deficiency and lysosomal glycogen accumulation.
Alicia Khazzeka, Rebecca L. Koch, Jeong‐A. Lim, Jeremy D. Ward, Jessica Doxey, William R. Jeck, Priya S. Kishnani   +6 more
doaj   +1 more source

Crescimento e metabolismo do nitrogênio em juvenis de Trachinotus marginatus alimentados com diferentes níveis proteicos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2015
O objetivo deste trabalho foi avaliar o crescimento e alterações no metabolismo do nitrogênio, além da composição do fígado e do músculo de juvenis de pampo Trachinotus marginatus alimentados com 43, 54 ou 64% de proteína bruta (PB43, PB54 e PB64 ...
E.M. Silva, J.M. Monserrat, L.A. Sampaio, M.B. Tesser   +3 more
doaj   +1 more source