Results 71 to 80 of about 10,864 (249)

Seroprevalence and biochemical parameters among patients with Chikungunya in Adamaoua region, Cameroon: A cross‐sectional study

open access: yesPublic Health Challenges
Background Chikungunya virus (CHIKV) infection is a vector‐borne febrile illness endemic to Africa. In Cameroon, few studies have documented human exposure to CHIKV, especially in the Adamaoua region.
Lise Paule Djamko Toko   +4 more
doaj   +1 more source

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

Programmable Carrier‐Free All‐Enzyme Beads for Modular Continuous‐Flow Biocatalysis

open access: yesAdvanced Materials, EarlyView.
Genetically encoded enzyme building blocks self‐assemble into monodisperse, carrier‐free protein beads via a droplet‐based formulation strategy. These programmable catalytic particles enable modular continuous‐flow biocatalysis, from single‐enzyme reactions to multi‐enzyme cascades and bead–bead coupled reactor systems.
Jennifer Kühne   +12 more
wiley   +1 more source

Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis

open access: yesAdvanced Science, EarlyView.
Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang   +9 more
wiley   +1 more source

TRANSAMINASE IN HUMAN SEMEN [PDF]

open access: yesReproduction, 1967
Summary. Determinations of aspartate and alanine aminotransferase activity in human semen were carried out by the spectrophotometric and colorimetric methods. It was found that the occurrence of interfering substances in semen makes the spectrophotometric method unsuitable without prior partial purification of the enzyme.
openaire   +2 more sources

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

open access: yesAdvanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu   +17 more
wiley   +1 more source

Structural studies into ketosteroid dehydrogenases and S-selective ω-transaminases [PDF]

open access: yes, 2016
In this thesis we studied the 3D-structures of three different proteins by protein X-ray crystallography. The knowledge obtained from the 3D-structures of the proteins is combined with biochemical data to discover the details of the functioning of the ...
van Oosterwijk, Cornelis Christiaan
core   +3 more sources

Role of Glutamine Transaminases in Nitrogen, Sulfur, Selenium, and 1-Carbon Metabolism

open access: yes, 2014
Glutamine metabolism is largely controlled by two enzyme pathways: 1) Conversion of glutamine to glutamate catalyzed by glutaminases, followed by conversion of glutamate to α-ketoglutarate by a glutamate-linked aminotransferases (or by the action of ...
Dorai, Thambi   +13 more
core   +1 more source

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

open access: yesAdvanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu   +13 more
wiley   +1 more source

SERUM PROTEINS, TRANSAMINASES AND PHOSPHATASES IN MALNUTRITION [PDF]

open access: yes, 1976
The levels of serum tota1 protein, albumin, transaminases and phosphatases were estimated in a group of children with severe Marasmus or mild malnutrition in order to identify some of the associated deficiencies in these syndromes.
H. Mohammadiha   +3 more
core  

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