Results 51 to 60 of about 122,944 (342)

Hepatitis B in Pediatric Population: Observational Retrospective Study in Romania

Life
Hepatitis B virus (HBV) is a frequent cause of chronic hepatitis worldwide, with an estimated 5.6 million children under 5 years being infected. In Romania, there are no available epidemiology reports on large cohorts in children.
Daniela Păcurar, Alexandru Dinulescu, Gheorghiță Jugulete, Alexandru-Sorin Păsărică, Irina Dijmărescu   +4 more
doaj   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Hepatotoxicity Evaluation of Aqueous Extract from Scutia buxifolia

Molecules, 2013
Nowadays there is an increase in the number of people taking herbals worldwide. Scutia buxifolia is used for the treatment of hypertension, but little is known about its action on liver.
Margareth Linde Athayde, Liliane de Freitas Bauermann, Isabel Cristina da Costa Araldi, Rafael Noal Moresco, Helena Kober, Roberta da Silva Jesus, Carolina Fantinel Veloso, Mariana Piana, Thiele Faccim de Brum, Aline Augusti Boligon, Bruno Tomazele Rovani, Robson Borba de Freitas   +11 more
doaj   +1 more source

The clinical profile, hematological parameters and liver transaminases of dengue NS1 Ag positive patients admitted to Jaffna Teaching Hospital, Sri Lanka

BMC Research Notes, 2019
Objective of the study is to evaluate the on-admission day symptoms and signs, clinical, hematological parameters and liver transaminases of the dengue NS1 positive patients who got admitted on different clinical phases [Febrile phase (day 1–3) and ...
T. Jayadas, T. Kumanan, V. Arasaratnam, K. Gajapathy, S. N. Surendran   +4 more
semanticscholar   +1 more source

CASCAT: Redesign of omega-Transaminases for Synthesis of Chiral Amines☆

, 2010
Transaminases (EC 2.6.1.18) are attractive biocatalysts for synthesis of chiral amines and alpha-amino acids. These enzymes catalyze transfer of an amine group from a donor substrate to an acceptor compound using the cofactor pyridoxal-5′-phoshate (PLP).
Engelmark Cassimjee, Karim,, V. Abedi, Svedendahl, Maria,, Branneby, C., C. Branneby, K.E. Cassimjee, P. Berglund, M. Svedendahl, Berglund, Per,, Wells, A., Abedi, V., A. Wells   +11 more
core   +1 more source

Real‐World Longitudinal Data on the Impact of Hydroxychloroquine Blood Level Monitoring on Lupus Outcomes: Results of a Prospective Longitudinal Cohort Study

Arthritis Care &Research, EarlyView.
Objective Hydroxychloroquine (HCQ) is a cornerstone therapy in systemic lupus erythematosus (SLE), but the weight‐based dosing does not account for clinical factors that can introduce individual variability in drug metabolism and clearance. We leveraged longitudinal data from a prospective SLE cohort to identify clinical factors that predict ...
Jay J. Patel, Fauzia Hollangel, Caroline Packee, Amita Kapoor, Brad Rovin, Nathalie Costedoat‐Chalumeau, Shivani Garg   +6 more
wiley   +1 more source

Routine Laboratory Parameter Dynamics and Laboratory Adverse Events in Psoriasis Patients on Long-term Treatment with Adalimumab, Etanercept, and Ustekinumab

Acta Dermato-Venereologica, 2017
Only limited data on laboratory parameter dynamics and safety under prolonged biologic treatment in a “real-world” scenario are available for recommendations on screening and monitoring.
Jochen H. Hoffmann, Christian Knoop, Alexander H. Enk, Eva N. Hadaschik   +3 more
doaj   +1 more source

The effect of isotretinoin on triglycerides and liver aminotransferases Influência da isotretinoína nas transaminases hepáticas e triglicerídeos

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Isotretinoin has been used to treat the most severe cases of acne; however, it may provoke adverse events in mucocutaneous and hepatic tissues, lead to alterations in lipid levels and cause teratogenicity.
Andreia Salezze Vieira, Vanessa Beijamini, Ana Carolina Melchiors   +2 more
doaj   +1 more source

The protective effect of Coriandrum sativum L. oil against liver toxicity induced by Ibuprofen in rats. [PDF]

Journal of Bioscience and Applied Research, 2016
Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and in inflammation.Coriandrum sativum is cultivated for its aromatic and medicinal uses.
Hoda H. Baghdadi, Fatma M. El-Demerdash, Sodfa Hussein, Eman H. Radwan   +3 more
doaj   +1 more source

A clinical case of diagnosis of autoimmune hepatitis at the stage of liver cirrhosis

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
The aim of the work is to analyze a clinical case of autoimmune hepatitis (АІН) diagnosis at the stage of cirrhosis in a 40-year-old female patient and to remind practicing doctors about the serious consequences of this disease. Materials and methods.
O. A. Svitlytska, O. V. Riabokon, A. O. Svitlytskyі, N. H. Horbatkova, E. V. Kotliarevska   +4 more
doaj   +1 more source