High dose atorvastatin associated with increased risk of significant hepatotoxicity in comparison to simvastatin in UK GPRD cohort [PDF]
Background and Aims: Occasional risk of serious liver dysfunction and autoimmune hepatitis during atorvastatin therapy has been reported. We compared the risk of hepatotoxicity in atorvastatin relative to simvastatin treatment.
Clarke, Alan T. +4 more
core +3 more sources
EFFECT OF PIGEON ORIGIN NEWCASTLE DISEASE VIRUS ON VARIOUS LIVER ENZYMES AND ASSOCIATED PATHOLOGICAL CHANGES IN EXPERIMENTALLY INFECTED PIGEONS [PDF]
Newcastle disease virus (NDV) was isolated from a field outbreak in pigeons. The virus was characterized by haemagglutination test (HA) and confirmed by haemagglutination inhibition test (HAI).
I. MUSHTAQ, F. RIZVI AND M. S. ULLAH
doaj
Effect of Wakame and Carob Pod Snacks on Non-Alcoholic Fatty Liver Disease [PDF]
Snacks combining different functional ingredients could represent a useful therapeutic strategy against NAFLD. The present study aimed to analyze the effect of two snack formulations based on carob and wakame flour in the treatment for NAFLD in rats. For
Aguirre López, Leixuri +6 more
core +3 more sources
Antioxidant, hypoglycemic, and hepatoprotective effect of aqueous and ethyl acetate extract of carob honey in streptozotocin -induced diabetic rats [PDF]
Aim: The aim of the study included the effect of aqueous extract (AE) and ethyl acetate extract (EAE) on blood sugar in diabetic rats and their effects on liver enzymes and lipid panel in control and diabetic rats.
Redouan El-Haskoury +4 more
doaj +1 more source
Clinical features of chronic hepatitis C in children
The problem of chronic viral hepatitis C is one of the most urgent in modern medicine. This cannot but concern the child population, which is the most vulnerable. Under supervision were 50 children under 18 years of age who were treated in the infectious
M. S. Bokhonov +3 more
doaj +1 more source
Fatal lymphoproliferation and acute monocytic leukemia-like disease following infectious mononucleosis in the elderly [PDF]
Three elderly patients are reported, in whom serologically confirmed recent infectious mononucleosis is followed by fatal lymphoproliferation (case 1), by acute monocytic leukemia (case 2), and by acute probably monocytic leukemia (case 3)
Deinhardt, F. +5 more
core +1 more source
Transaminases in Shigellæ [PDF]
NUMEROUS investigations have been made of the transaminase system in bacteria, and these have been reviewed by Meister1. The only reference to the transaminase activity in Shigellae appears to be the one mentioned by Lichstein and Cohen2 on a strain of Shigella dysenteriae (Shiga).
openaire +2 more sources
The interaction between diabetes, body mass index, hepatic steatosis, and risk of liver resection: insulin dependent diabetes is the greatest risk for major complications [PDF]
Background. This study aimed to assess the relationship between diabetes, obesity, and hepatic steatosis in patients undergoing liver resection and to determine if these factors are independent predictors of major complications.
Aroori, S +5 more
core +3 more sources
Reduced lysosomal acid lipase activity: A new marker of liver disease severity across the clinical continuum of non-alcoholic fatty liver disease? [PDF]
Lysosomal acid lipase (LAL) plays a key role in intracellular lipid metabolism. Reduced LAL activity promotes increased multi-organ lysosomal cholesterol ester storage, as observed in two recessive autosomal genetic diseases, Wolman disease and ...
Angelico, F +7 more
core +1 more source
Role of gemcitabine in the treatment of advanced and metastatic breast cancer [PDF]
Gemcitabine is an antimetabolite drug with proven antitumor activity and tolerability in metastatic breast cancer. In a total of nine studies, gemcitabine monotherapy has reached response rates of up to 37% in the first-line setting, 26% in the second ...
Heinemann, Volker
core +1 more source

