Results 31 to 40 of about 10,864 (249)

Hepatitis B in Pediatric Population: Observational Retrospective Study in Romania

Life
Hepatitis B virus (HBV) is a frequent cause of chronic hepatitis worldwide, with an estimated 5.6 million children under 5 years being infected. In Romania, there are no available epidemiology reports on large cohorts in children.
Daniela Păcurar, Alexandru Dinulescu, Gheorghiță Jugulete, Alexandru-Sorin Păsărică, Irina Dijmărescu   +4 more
doaj   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Hepatotoxicity Evaluation of Aqueous Extract from Scutia buxifolia

Molecules, 2013
Nowadays there is an increase in the number of people taking herbals worldwide. Scutia buxifolia is used for the treatment of hypertension, but little is known about its action on liver.
Margareth Linde Athayde, Liliane de Freitas Bauermann, Isabel Cristina da Costa Araldi, Rafael Noal Moresco, Helena Kober, Roberta da Silva Jesus, Carolina Fantinel Veloso, Mariana Piana, Thiele Faccim de Brum, Aline Augusti Boligon, Bruno Tomazele Rovani, Robson Borba de Freitas   +11 more
doaj   +1 more source

Membrane-immobilized transaminases for the synthesis of enantiopure amines [PDF]

For the manufacture of enantiopure amines, greener synthesis processes are needed. Transaminases (TAs) are able to produce chiral amines with excellent enantioselectivity and in mild conditions, and can be immobilized to target stability, recoverability,
David, Roura Padrosa, Xuan Dieu Linh, Nguyen, Tom, Leyssens, Hippolyte, Meersseman Arango, Francesca, Paradisi, Damien, Debecker, Patricia, Luis   +6 more
core   +2 more sources

Detoxification of Fumonisins by Three Novel Transaminases with Diverse Enzymatic Characteristics Coupled with Carboxylesterase

, 2023
Fumonisin (FB) is one of the most common mycotoxins contaminating feed and food, causing severe public health threat to human and animals worldwide.
Tongcun Zhang, Xuegang Luo, Junhao Sun, Mengwei Zhang, Kungang Pan, Junqi Zhao, Yue Wang, Tianhui Liu, Zhongyuan Li   +8 more
core   +1 more source

Developing and Evaluating a Laboratory‐Based Frailty Index for the Prediction of Long‐Term Health Outcomes in Systemic Lupus Erythematosus

Arthritis Care &Research, EarlyView.
Objective We aimed to construct and evaluate the first laboratory‐based frailty index (FI‐Lab) for predicting adverse outcomes in systemic lupus erythematosus (SLE) and to compare its predictive ability to that of an existing clinical FI. Methods We used data from a single‐center prospective cohort of adult patients with SLE whose baseline visit ...
Grace Burns, Samuel D. Searle, Alexandra Legge   +2 more
wiley   +1 more source

Routine Laboratory Parameter Dynamics and Laboratory Adverse Events in Psoriasis Patients on Long-term Treatment with Adalimumab, Etanercept, and Ustekinumab

Acta Dermato-Venereologica, 2017
Only limited data on laboratory parameter dynamics and safety under prolonged biologic treatment in a “real-world” scenario are available for recommendations on screening and monitoring.
Jochen H. Hoffmann, Christian Knoop, Alexander H. Enk, Eva N. Hadaschik   +3 more
doaj   +1 more source

The effect of isotretinoin on triglycerides and liver aminotransferases Influência da isotretinoína nas transaminases hepáticas e triglicerídeos

Anais Brasileiros de Dermatologia, 2012
BACKGROUND: Isotretinoin has been used to treat the most severe cases of acne; however, it may provoke adverse events in mucocutaneous and hepatic tissues, lead to alterations in lipid levels and cause teratogenicity.
Andreia Salezze Vieira, Vanessa Beijamini, Ana Carolina Melchiors   +2 more
doaj   +1 more source

The protective effect of Coriandrum sativum L. oil against liver toxicity induced by Ibuprofen in rats. [PDF]

Journal of Bioscience and Applied Research, 2016
Ibuprofen (IBU) is a Non-steroidal anti-inflammatory drugused in the treatment of pain, fever and in inflammation.Coriandrum sativum is cultivated for its aromatic and medicinal uses.
Hoda H. Baghdadi, Fatma M. El-Demerdash, Sodfa Hussein, Eman H. Radwan   +3 more
doaj   +1 more source

A clinical case of diagnosis of autoimmune hepatitis at the stage of liver cirrhosis

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2023
The aim of the work is to analyze a clinical case of autoimmune hepatitis (АІН) diagnosis at the stage of cirrhosis in a 40-year-old female patient and to remind practicing doctors about the serious consequences of this disease. Materials and methods.
O. A. Svitlytska, O. V. Riabokon, A. O. Svitlytskyі, N. H. Horbatkova, E. V. Kotliarevska   +4 more
doaj   +1 more source