Results 11 to 20 of about 122,944 (342)

Comparison of Four Immobilization Methods for Different Transaminases

open access: yesCatalysts, 2023
Biocatalytic syntheses often require unfavorable conditions, which can adversely affect enzyme stability. Consequently, improving the stability of biocatalysts is needed, and this is often achieved by immobilization.
Tobias Heinks   +6 more
semanticscholar   +2 more sources

Measurement of Transaminases in Serum

open access: yesNature, 1960
WITH the growing emphasis on the study of glutamic oxaloacetic and glutamic pyruvic transaminases of the serum, both in the diagnosis and the prognosis of a large number of pathological conditions, particularly in cardiovascular and hepatic diseases, a need for a simple and accurate method for the measurement of these transaminases is apparent.
Yatzidis, H.
openaire   +4 more sources

Self-Sufficient Flow-Biocatalysis by Coimmobilization of Pyridoxal 5′-Phosphate and ω-Transaminases onto Porous Carriers

open access: yesACS Sustainable Chemistry and Engineering, 2018
We expanded the application of self-sufficient heterogeneous biocatalysts containing coimmobilized ω-transaminases and pyridoxal 5′-phosphate (PLP) to efficiently operate packed-bed reactors in continuous flow.
A. I. Benítez-Mateos   +4 more
semanticscholar   +3 more sources

Transaminases for chiral amine synthesis. [PDF]

open access: yesCurrent Opinion in Chemical Biology, 2018
Amine transaminases are important biocatalysts for the synthesis of chiral primary amines. Unlike many enzymes that have been employed for the synthesis of optically active amines, amine transaminases are capable of asymmetric synthesis and do not rely ...
A. Gomm, Elaine O’Reilly
semanticscholar   +2 more sources

Therapy of acute hepatitis C infection [PDF]

open access: yesVojnosanitetski Pregled, 2005
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj   +1 more source

Effect of Exercise Training on Serum Transaminases in Patients With Nonalcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis

open access: yesFrontiers in Physiology, 2022
Background/Purpose: Nonalcoholic fatty liver disease (NAFLD) constitutes a spectrum of liver diseases associated with various metabolic disorders. Exercise interventions reportedly manage the clinical outcomes of NAFLD, but their efficacy depends on ...
Feng Hong   +6 more
semanticscholar   +1 more source

Predicting and grading liver injury in the absence of computed tomographic imaging

open access: yesJournal of Family Medicine and Primary Care, 2023
Background: Even developed countries lack computed tomography (CT) scan in rural areas. Availability, affordability and accessibility of CT scan play an important role in the management of blunt hepatic trauma.
Mario Victor Newton, S. G. Subramanyam
doaj   +1 more source

Protein engineering of amine transaminases

open access: yesFrontiers in Catalysis, 2022
Protein engineering is a powerful and widely applied tool for tailoring enzyme properties to meet application-specific requirements. An attractive group of biocatalysts are PLP-dependent amine transaminases which are capable of converting prochiral ...
Qinglong Meng   +3 more
semanticscholar   +1 more source

Gunshot liver injuries grade I-III and related liver enzyme values [PDF]

open access: yesVojnosanitetski Pregled, 2018
Background/Aim. The liver is one of the most commonly injured solid organ in patients with abdominal gunshot wounds. The aim of this study was to investigate correlation between aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels ...
Radunović Miodrag   +4 more
doaj   +1 more source

Using Steady-State Kinetics to Quantitate Substrate Selectivity and Specificity: A Case Study with Two Human Transaminases

open access: yesMolecules, 2022
We examined the ability of two human cytosolic transaminases, aspartate aminotransferase (GOT1) and alanine aminotransferase (GPT), to transform their preferred substrates whilst discriminating against similar metabolites.
Alessio Peracchi, Eugenia Polverini
doaj   +1 more source

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