Results 1 to 10 of about 45,783 (265)

Using Steady-State Kinetics to Quantitate Substrate Selectivity and Specificity: A Case Study with Two Human Transaminases

Molecules, 2022
We examined the ability of two human cytosolic transaminases, aspartate aminotransferase (GOT1) and alanine aminotransferase (GPT), to transform their preferred substrates whilst discriminating against similar metabolites.
Eugenia Polverini, Alessio Peracchi, Peracchi Alessio   +2 more
exaly   +3 more sources

Elevated Transaminases: Does It Always Warrant a Liver Biopsy? Lessons Learned From Pompe Disease [PDF]

JIMD Reports
Pompe disease (PD) is an autosomal recessive disorder caused by pathogenic variants in GAA, resulting in acid alpha‐glucosidase (GAA) deficiency and lysosomal glycogen accumulation.
Alicia Khazzeka, Rebecca L. Koch, Jeong‐A. Lim, Jeremy D. Ward, Jessica Doxey, William R. Jeck, Priya S. Kishnani   +6 more
doaj   +2 more sources

Expanding the phenotype of neurological manifestations of dengue fever: Acute necrotizing encephalopathy

Indian Pediatrics Case Reports, 2021
Background: Neurological manifestations following dengue fever are increasingly reported and include encephalopathy, encephalitis, neuro-ophthalmic manifestations or Guillain–Barre syndrome-like presentation.
Arpit Mittal, Sonu Kumar, Radhamohan Rana, Jaya Shankar Kaushik   +3 more
doaj   +1 more source

Role of Nutrition in the Etiopathogenesis and Prevention of Nonalcoholic Fatty Liver Disease (NAFLD) in a Group of Obese Adults

Medicina, 2023
Nonalcoholic fatty liver disease (NAFLD) is liver damage characterized by an accumulation of triglycerides in hepatocytes of >5% (due to an alteration of the balance of the lipid metabolism in favour of lipogenesis compared to lipolysis) that is not ...
Daniela Metro, Martina Buda, Luigi Manasseri, Francesco Corallo, Davide Cardile, Viviana Lo Buono, Angelo Quartarone, Lilla Bonanno   +7 more
doaj   +1 more source

Effects of folic acid supplementation on liver enzymes, lipid profile, and insulin resistance in patients with non-alcoholic fatty liver disease: A randomized controlled trial

Advanced Biomedical Research, 2023
Background: Previous evidence revealed an association between folate deficiency and non-alcoholic fatty liver disease (NAFLD). This study is the first one investigating the effects of folic acid on hepatic steatosis grade, liver enzymes, insulin ...
Mohamad Reza Molaqanbari, Shadi Zarringol, Hamid Reza Talari, Mohsen Taghizadeh, Fereshteh Bahmani, Abbas Mohtashamian, Armin Ebrahimzadeh, Nasrin Sharifi   +7 more
doaj   +1 more source

Therapy of acute hepatitis C infection [PDF]

Vojnosanitetski Pregled, 2005
Background. Hepatitis C viral infection is a major cause of chronic hepatitis, liver cirrhosis and hepatocellular carcinoma. The progression of acute to chronic infection occurs in 50-90% of cases.
Đokić Milomir, Begović Vesna
doaj   +1 more source

Predicting and grading liver injury in the absence of computed tomographic imaging

Journal of Family Medicine and Primary Care, 2023
Background: Even developed countries lack computed tomography (CT) scan in rural areas. Availability, affordability and accessibility of CT scan play an important role in the management of blunt hepatic trauma.
Mario Victor Newton, S. G. Subramanyam
doaj   +1 more source

Gunshot liver injuries grade I-III and related liver enzyme values [PDF]

Vojnosanitetski Pregled, 2018
Background/Aim. The liver is one of the most commonly injured solid organ in patients with abdominal gunshot wounds. The aim of this study was to investigate correlation between aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels ...
Radunović Miodrag, Vuković Marko, Radojević Nemanja, Lazović Ranko, Radunović Miroslav   +4 more
doaj   +1 more source

Hepatobiliary Involvement in Neonates With COVID-19 Infection: A Previous Case Series Studies [PDF]

Journal of Pediatrics Review, 2023
Background: The most common symptoms in neonates with severe COVID-19 infection have been respiratory problems. The virus may adversely affect organs such as the liver.
Roya Farhadi
doaj  

Prognostic Value of Transaminases and Bilirubin Levels at Admission to Hospital on Disease Progression and Mortality in Patients with COVID-19—An Observational Retrospective Study

Pathogens, 2022
Introduction: Given the impact of COVID-19 on the world healthcare system, and the efforts of the healthcare community to find prognostic factors for hospitalization, disease progression, and mortality, the aim of the present study was to investigate the
Antonio Russo, Mariantonietta Pisaturo, Roberta Palladino, Paolo Maggi, Fabio Giuliano Numis, Ivan Gentile, Vincenzo Sangiovanni, Vincenzo Esposito, Rodolfo Punzi, Giosuele Calabria, Carolina Rescigno, Angelo Salomone Megna, Alfonso Masullo, Elio Manzillo, Grazia Russo, Roberto Parrella, Giuseppina Dell’Aquila, Michele Gambardella, Antonio Ponticiello, Nicola Coppola, on behalf of CoviCam Group   +20 more
doaj   +1 more source