Results 171 to 180 of about 122,944 (342)

Surfaceome Reprogramming of Stemsomes Promotes Lung Cancer Targeting via Potentiated Receptor–Ligand Interactions

open access: yesAdvanced Science, EarlyView.
This study presents a surfaceome‐reprogramming strategy for mutation‐independent lung cancer therapy by repurposing dexamethasone to prime mesenchymal stem cell‐derived nanovesicles. The engineered vesicles leverage multi‐valent interactions mediated by upregulated adhesion proteins, EPHA2, and NOTCH3.
Geunhye Kim   +8 more
wiley   +1 more source

The Effect of De-Fatted Moringa Oleifera Seed Powder on Growth Rate and some Biochemical Parameters of Albino Rats

open access: yesThe Bioscientist, 2013
The nutritional and therapeutic properties of Moringa oleifera cannot be overemphasized, since all the parts of the plant (leaves, seeds, root, bark, pods etc.) have been reported to possess antibiotic, anti-hypertensive, anti-tumor and anti-oxidative ...
I. O Igwilo   +5 more
doaj  

Circulating Amino Acid Network Remodeling Reveals Systemic Metabolic Reprogramming Predictive of Colorectal Cancer Recurrence and Metastasis

open access: yesAdvanced Science, EarlyView.
Blood‐based amino acid patterns measured by 19F NMR reveal hidden metabolic changes in colorectal cancer. By analyzing how these amino acids interact as a network, machine learning models identify patients at higher risk of recurrence and metastasis.
Ji‐Yeon Lee   +9 more
wiley   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

open access: yesAdvanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu   +12 more
wiley   +1 more source

Hypertransaminasemia Is a Marker of Severity in Children Hospitalized for Influenza. [PDF]

open access: yesInfluenza Other Respir Viruses
Poeta M   +17 more
europepmc   +1 more source

Effect of Mercuric Chloride on Hepatic Phosphatases and Transaminases in Albino Rat

open access: yes, 2012
Mercuric chloride is a serious health hazard and produces various disorders. However, phosphatases and transaminases are marker enzymes of hepatic toxicity. Twenty four adult albino rats have taken and divided into 4 groups.
Mahour, K., Saxena, P. N.
core  

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

open access: yesAdvanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo   +5 more
wiley   +1 more source

Engineering of ω-transaminases for advanced applications. [PDF]

open access: yesAppl Microbiol Biotechnol
Wegner U, von Wirén N, Kunze G.
europepmc   +1 more source

TRANSAMINASE AND PYRIDOXINE DEFICIENCY

open access: yesJournal of Biological Chemistry, 1947
S R, AMES, P S, SARMA, C A, ELVEHJEM
openaire   +2 more sources

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