Results 191 to 200 of about 10,864 (249)
Advanced Science, EarlyView.Nebulized BN@NF nanozymes integrate boron nanosheets with Nd‐doped iron phosphide to form a sono‐magneto‐responsive Z‐scheme heterostructure. Under ultrasound and magnetic activation, BN@NF amplifies ROS generation, eradicates bacteria, disrupts biofilms, and reshapes pulmonary inflammation through NF‐κB suppression, mitophagy promotion, and M1‐to‐M2 ...
Xiaofeng Luo +6 more
wiley +1 more source
Advanced Science, EarlyView.Sepsis‑induced pediatric acute respiratory distress syndrome suppresses FOXF1 in lung endothelial cells which causes life‐threatening lung damage. To counter this, researchers developed nanoparticles that specifically target these cells and deliver FOXF1 mRNA.
Zicheng Deng +14 more
wiley +1 more source
Advanced Science, EarlyView.A HER3‐targeted sonogenetic lipid nanoparticle platform is developed for triple‐negative breast cancer therapy. An AI‐designed miniprotein inhibits HER3 signaling, while TRPV4 and NFAT‐responsive IL‐15 plasmids enable ultrasound‐controlled calcium signaling and cytokine expression. The system induces Ca2+ overload, ROS generation, mitochondrial damage,
Junya Song +6 more
wiley +1 more source
Direct Conversion of Hydrazones to Amines using Transaminases [PDF]
ChemCatChem, 2021 Transaminase enzymes (TAms) have been widely used for the amination of aldehydes and ketones, often resulting in optically pure products. In this work, transaminases were directly reacted with hydrazones in a novel approach to form amine products ...
Helen C Hailes +2 more
exaly +3 more sources
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The Journal of Parasitology, 1960
Although transaminases were identified in animal tissues as early as 1937, very few observations have been made on these systems in parasitic helminths. Daugherty (1952) found that homogenates of the liver fluke, Fasciola hepatica, contained very high transaminase activity.
G, WERTHEIM, R, ZELEDON, C P, READ
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Although transaminases were identified in animal tissues as early as 1937, very few observations have been made on these systems in parasitic helminths. Daugherty (1952) found that homogenates of the liver fluke, Fasciola hepatica, contained very high transaminase activity.
G, WERTHEIM, R, ZELEDON, C P, READ
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Transaminases in the acquired pellicle
Archives of Oral Biology, 2009Transaminases (AST, aspartate amino transferase; ALT, alanine amino transferase) are relevant enzymes in physiology and pathology of the human organism. The aim of the present in situ study was to demonstrate the presence of these enzymes in the enamel pellicle.Bovine enamel slabs were fixed on buccal sites of individual upper jaw splints and worn for ...
Hannig, Christian +2 more
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Affinity chromatography of transaminases
Analytical Biochemistry, 1971Abstract It is shown that glutamic-oxaloacetic transaminase from pig heart can be selectively and reversibly bound to a Sepharose column substituted with N′-alkyl derivatives of pyridoxamine 5′-phosphate. A simple procedure is described which includes formation of apotransaminase, its binding to the substituted Sepharose, and its elution under the ...
R, Collier, G, Kohlhaw
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Transaminases for Pyridoxamine and Purines
Nature, 1952BRAUNSTEIN'S1 demonstration of the transaminase reaction as a mode of formation of ammo-acids has been broadened recently to include a wide variety of transaminases in bacteria2, animal tissues3 and plants4. In the present communication, we wish to report the formation of compounds other than amino-acids by the transaminase reaction.
C F, GUNSALUS, J, TONZETICH
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