Results 261 to 270 of about 114,148 (343)

.BETA.3-adrenoceptor-mediated increased circulating transaminase levels in mice treated with its agonist BRL 37344

, 2010
Hiroko Kasahara, Shin-ichi MUTO, Yoshiyuki Motokawa, Nobuhiko Arisaka, Sayaka Kobayashi, Shinji Souma, Junji Kuroda   +6 more
openalex   +2 more sources

Synergistic Activation of Immunogenic Cell Death and the cGAS–STING Pathway by Engineered Zinc/Manganese‐Based Metal–Organic Framework Nanoplatforms for Colon Cancer Immunotherapy

Advanced Science, EarlyView.
A zinc/manganese (Zn/Mn)‐based metal‐organic framework (MOF) loaded with the STING agonist c‐di‐AMP diammonium (denoted AMP@Zn/Mn‐MOF) was developed to synergistically activate the cGAS‐STING pathway and induce immunogenic cell death. This nanoplatform reprograms the immunosuppressive tumor microenvironment, significantly enhancing anti‐PD‐L1 ...
Bingzi Zhu, Xiaodong Chen, Chang Xu, Xuehua Qian, Binglong Bai, Ji Lin, Wenhai Deng, Xiang Wang, Yuekai Cui, Shengsheng Zhao, Zuoliang Xie, Tao You, Yingpeng Huang, Xian Shen, Xufeng Lu, Weijian Sun   +15 more
wiley   +1 more source

Isolated IgG elevation in patients with persistently normal transaminases does not affect the outcome of autoimmune hepatitis. [PDF]

JHEP Rep
Díaz-González Á, Schregel I, Carballo L, Álvarez-Navascués C, Frisancho-Morales E, Miquel M, Retortillo MG, Gómez J, Horta D, Mateos B, Engel B, Volmer F, Barrio MD, Rodríguez-Tajes S, Olivas I, Hartl J, González CA, Hernández-Guerra M, Castello I, Pérez-Medrano I, González-Santiago JM, Arencibía A, Gómez A, Rodríguez-Perálvarez M, Crespo J, Sala M, Salcedo M, Barreira-Díaz A, Riveiro-Barciela M, Taubert R, Schramm C, Londoño MC, ColHai Registry.   +32 more
europepmc   +1 more source

Dendritic Nano‐Based Slippery Coating by Synergistic Mechanical and Electrostatic Interactions with Persistent and Exceptional Combats Thrombosis

Advanced Science, EarlyView.
A novel dendritic nano‐based slippery coating (DNSC), fabricated by encapsulating carboxyl silicone oil within amino dendritic silica nanoparticles and co‐embedding them in an epoxy resin matrix. The dendritic architecture enhances nanoparticle dispersion in the matrix and establishes mechanical interlock.
Shu Zhang, Yao Shen, Juan Liu, Qing Zeng, Yunze Ma, Shuping Chen, Taiyu Nan, Xiaoying Qiu, Jiayi Yu, Tao Fan, Guozhi Huang, Jihua Zou, Chengduan Yang   +12 more
wiley   +1 more source

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Hepatic Phenotype in NBAS-Associated Disease: Clinical Course, Prognostic Factors and Outcome in 230 Patients. [PDF]

Liver Int
Peters B, Schlieben LD, Brennenstuhl H, Arikan C, Bedoyan SM, Bulut FD, Crushell E, Dionisi-Vici C, Drab A, Fichtner A, Garcia AG, Fry D, Garbade SF, Hammann N, Hadzic N, Hegarty R, Jørgensen MH, Laaß M, Lainka E, Leghlam L, Lurz E, Mungan HNÖ, Pietrobattista A, Polo B, Socha P, Squires JE, Sun T, Vogel GF, Prokisch H, Kölker S, Hoffmann GF, Staufner C, Lenz D.   +32 more
europepmc   +1 more source

Metformin‐Based Covalent Organic Frameworks With Excellent Biosafety and High Efficiency against Pathogenic Microorganisms

Advanced Science, EarlyView.
This work presents the first metformin‐based COFs featuring built‐in biosafety and a unique triple‐synergy mechanism. This scalable platform achieves broad‐spectrum eradication of bacteria and viruses, enabling reusable protective membranes with exceptional biocompatibility for advanced biomedical applications and personal protection.
Jia‐Yi Liu, Hong Jiang, Lei Ma, Jin‐Yi Yu, Ming‐Yi Yang, Hao‐Ru Wang, Jun‐Yuang Tang, Shengfeng Huang, Wei Yi, Meng Lu, Ya‐Qian Lan, Xu‐Jia Hong   +11 more
wiley   +1 more source

The Usefulness of Basic Laboratory Analyses in Diagnostics of Inherited Metabolic Diseases in Children. [PDF]

Diagnostics (Basel)
Lipiński P, Doroba A.
europepmc   +1 more source

Versatile DNA Hydrogel‐Mediated Delivery of Ginsenoside‐Encapsulated Small Extracellular Vesicles to Boost Diabetic Wound Repair

Advanced Science, EarlyView.
This study presents a DNA hydrogel‐mediated delivery system, in which ginsenoside (GS) molecules are incorporated into small extracellular vesicles (sEV) secreted by mesenchymal stem cells (MSCs) and the formed complexes are then anchored in DNA hydrogels via aptamer‐CD63 affinity as “GS/sEV@DNAgels”, to improve diabetic wound repair.
Jianming Xing, Shuangyang Li, Yuning Wang, Xushuang Jia, Ruiting Lin, Xintong Liu, Dongxu Wang, Ning Cui, Peng Ji, Jiaqi Chen, Shengnian Wang, Guangzhe Li, Ye Teng, Da Liu, Ye Jin   +14 more
wiley   +1 more source

A case of secondary lymphangiectasia due to ancylostoma intestinal infection. [PDF]

Endoscopy
Cosenza A, Elli L, Maraschini A, Fracas E, Scaramella L.   +4 more
europepmc   +1 more source