Results 271 to 280 of about 137,846 (394)

GPD1 deficiency-a rare, overlooked cause of liver disease. [PDF]

open access: yesJ Hum Genet
Türk NE   +7 more
europepmc   +1 more source

Deep‐Learning Model for Central Nervous System Infection Diagnosis and Prognosis Using Label‐Free 3D Immune‐Cell Morphology in the Cerebrospinal Fluid

open access: yesAdvanced Intelligent Systems, EarlyView.
Early diagnosis and prognosis prediction of central nervous system infections are critical. This study introduces a deep‐learning model utilizing cerebrospinal fluid immune‐cell morphology captured via 3D holotomography. The model effectively predicts infection etiology and prognosis, achieving high accuracy.
Bo Kyu Choi   +5 more
wiley   +1 more source

Engineered Biocatalyst for Enantioselective Hydrazone Reduction

open access: yesAngewandte Chemie, EarlyView.
Here, we report the discovery and engineering of a hydrazone reductase (HRED) biocatalyst that promotes efficient reduction of protected hydrazones with exceptional stereocontrol. These biotransformations offer a sustainable strategy for synthesizing valuable chiral N─N containing products that are commonly found in pharmaceuticals and agrochemicals ...
Amy E. Hutton   +9 more
wiley   +2 more sources

Pregnancy does not affect liver chemistries in metabolic dysfunction-associated steatotic liver disease. [PDF]

open access: yesHepatol Commun
Finer Z   +7 more
europepmc   +1 more source

Case Report: Unusual Neurological Features of Leigh Syndrome due to m.8993T>G Pathogenic Variant in the MT‐ATP6 Gene

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT The MT‐ATP6 gene m.8993T>G pathogenic variant has been associated with Leigh syndrome, especially in patients exhibiting a high degree of heteroplasmy. Although patients may present with a wide phenotypic spectrum, characteristic findings include bilateral, symmetric hyperintensities in the basal ganglia and brainstem on brain MRI ...
Ramya Treitel   +2 more
wiley   +1 more source

Corrigendum: Hematological profile, inflammatory markers and serum liver enzymes in COVID 19 positive children vs. COVID 19 negative ones—a comparative study

open access: yesFrontiers in Pediatrics
Mirela Luminița Pavelescu   +8 more
doaj   +1 more source

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